Southern Africa’s Role in Human Evolution Unveiled
New genetic research is shedding light on some of the earliest chapters of our human history. In one…
AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
Development of a polygenic risk score for pelvic organ prolapse in Chinese women
Pelvic organ prolapse (POP), a condition whose development is shaped by both genetic and clinical risk factors, significantly…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
UK Biobank releases the world’s largest metabolomic dataset for disease research
UK Biobank has today [Thursday 20 November] released the final set of data on nearly 250 metabolites – the molecules in our blood produced by…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Subtle changes in the composition of short tandem repeats may shape disease risk
Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that…
Study links common Epstein-Barr virus to autoimmune lupus
One of humanity’s most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic lupus…
Stanford scientists discover unexpected cancer resistance in aged mice
Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led…
Study clarifies how biliary atresia overlaps with multiple congenital syndromes
Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or…