Scientists identify novel autoimmune driver behind DNA repair breakdown in childhood cancer
Researchers have found the first evidence for a previously unsuspected cause of pediatric cancer. They showed that children…
Tiny archaeon offers new clues to the minimum genetic requirements for life
Scientists have discovered a previously unknown microorganism, which has the smallest genome ever found, that is possibly able…
DNA Typewriter tracks cell divisions and developmental decisions in mice
Scientists have succeeded in reconstructing the family tree of cells in a developing mouse embryo. They recorded cells’…
New workflow rapidly identifies deadly fungal bloodstream infections
Bloodstream infections are a persistent threat to hospitalized patients, and those caused by fungi are particularly dangerous. Candida…
Cancer-related DNA changes may appear in blood years before diagnosis
Archived blood samples collected years before cancer diagnosis gave researchers a rare opportunity to examine whether molecular changes…
New prime assembly method enables long and precise DNA insertions
Genomic editing holds great potential yet continues to have its limitations. Most current methods either rely on untargeted gene…
Study identifies DNA loops as essential for tissue regeneration
After an injury, DNA not only alters its activity but also the way it is organized spatially within…
Study links heritability and polygenicity across complex human traits
Researchers at the University of Oslo have mapped which parts of our DNA carry the inherited differences behind…
Blood protein profiling could improve rare disease diagnosis
Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England…
Caloric restriction reduces genetic mutations across the mouse genome
Mutations are changes in the molecular “letters” that make up DNA, the genetic blueprint for cells. Mutations build…
New study reveals euchromatin forms dynamic condensed domains in cells
The human genome is about two meters long, yet it is folded inside a cell nucleus only about…
Ancient DNA Rewrites Story of Enigmatic ‘American Cheetah’
For several decades, paleontologists have described Miracinonyx trumani — an extinct species of cheetah-like felid that roamed the…