Researchers create the most detailed 3D maps of the human genome
In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators…
Nascent polypeptide-associated complex regulates early stages of protein formation
To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate…
Massive genetics study shows what truly separates and unites 14 psychiatric disorders
A sweeping genomic analysis reveals how psychiatric disorders cluster into five biological families, exposing shared pathways and pinpointing…
Southern Africa’s Role in Human Evolution Unveiled
New genetic research is shedding light on some of the earliest chapters of our human history. In one…
AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
Development of a polygenic risk score for pelvic organ prolapse in Chinese women
Pelvic organ prolapse (POP), a condition whose development is shaped by both genetic and clinical risk factors, significantly…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
UK Biobank releases the world’s largest metabolomic dataset for disease research
UK Biobank has today [Thursday 20 November] released the final set of data on nearly 250 metabolites – the molecules in our blood produced by…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Subtle changes in the composition of short tandem repeats may shape disease risk
Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that…