Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
UK Biobank releases the world’s largest metabolomic dataset for disease research
UK Biobank has today [Thursday 20 November] released the final set of data on nearly 250 metabolites – the molecules in our blood produced by…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Subtle changes in the composition of short tandem repeats may shape disease risk
Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that…
Study links common Epstein-Barr virus to autoimmune lupus
One of humanity’s most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic lupus…
Stanford scientists discover unexpected cancer resistance in aged mice
Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led…
Study clarifies how biliary atresia overlaps with multiple congenital syndromes
Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or…
Researchers Using Neanderthal DNA to Learn More About How Human Faces Develop and Evolve
University of Edinburgh scientist Hannah Long and colleagues show how a region of Neanderthal DNA is better at…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Genomic mapping of resistance mutations in A. baumannii
The bacteria Acinetobacter baumannii (A. baumannii) is a haunting presence in many hospitals in the United States, where more…
Researchers refine tools to map DNA’s 3D structure inside cells
DNA isn’t just a long string of genetic code, but an intricate 3D structure folded inside each cell.…
Two main methods for discovering disease genes reveal distinct aspects of biology
The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While…