New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
Genetic signals reveal why erectile dysfunction develops and who is most at risk
New genomic evidence unmasks the biological pathways driving erectile dysfunction, linking cardiometabolic disease and addiction traits to ED…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Study clarifies how biliary atresia overlaps with multiple congenital syndromes
Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or…
The caffeine conundrum in rapid depression treatments
Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic…
Blood protein pattern linked to increased risk of hereditary atherosclerosis
A specific pattern of proteins in the blood may reflect an increased risk of hereditary atherosclerosis. This is…
Global Virus Network announces the addition of three new Centers of Excellence
The Global Virus Network (GVN), a coalition of leading medical virologists representing 80+ Centers of Excellence and Affiliates…
Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease
A global research team has pinpointed the enzyme fueling hydrogen production in healthy guts and shown how its…
Genetic inflammatory signature defines depression subtypes and treatment response
Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that…
Exercise can mitigate depression-like behaviors induced by high-fat, high-sugar diets
Researchers led by Professor Yvonne Nolan at University College Cork have identified specific metabolic pathways through which exercise…