Paternal sperm epigenetics may help explain early pregnancy loss
When a pregnancy ends early and unexplained, the search for answers usually begins with the mother. Lacey Luense,…
Pediatric rheumatic diseases have unique genetic architecture compared to adults
Researchers from Children’s Hospital of Philadelphia (CHOP) have found that pediatric-onset rheumatic and inflammatory diseases have distinct genetic…
Comprehensive brain cell map opens new avenues for Alzheimer’s therapies
The brain’s immune cells are increasingly recognized as key players in Alzheimer’s disease, but exactly how they change…
Circular eccDNA shows potential to predict early-stage LUAD recurrence
LUAD is the most common histological subtype of lung cancer. Although surgery can be curative for patients diagnosed…
New computational technique traces ghost ancestry in modern human genomes
UC Berkeley researchers have identified regions of DNA that humans inherited from two unknown ancestors as a result…
Taste preference genes drive overeating and metabolic disease risk
Ever wonder why some people crave sweets while others can take them or leave them? Preliminary findings from…
Taiwan Biobank data reveals ongoing natural selection in living humans
For more than a century, scientists have sought to reconstruct human evolution using diverse lines of evidence, including…
Occult hepatitis B mutations drive liver cancer growth via Akt mTOR pathway
Occult hepatitis B virus (OBI) infection presents a significant global health challenge, notoriously flying under the radar of…
New ctDNA blood test improves personalized prostate cancer treatment
A noninvasive DNA blood test can identify metastatic castration-resistant prostate cancer (mCRPC) patients who are most likely to…
Genome-mining tool reveals new antibiotic hidden in a silent gene cluster
By combining multiple measures of biosynthetic similarity, DiscERN uncovered a silent gene cluster that produces discomycin A, offering…
Pet gecko offers promising model for cancer research breakthroughs
A new study, led by experts at the University of Nottingham, suggests a pet gecko with an unusually…
Integrating gene signatures and multi omics improves liver cancer treatment
Hepatocellular carcinoma (HCC) remains highly fatal due to late diagnosis and scarce early biomarkers. Multi‑omics and liquid biopsy…