Early RSV infection turns maternal allergy into a powerful driver of childhood asthma
By combining nationwide health data with elegant immunology experiments, researchers reveal how RSV infection in infancy hijacks maternal…
International collaboration develops STREAMS to standardize microbiome data
Microbiomes, the communities of microorganisms that live in and around us, play a vital role in everything from…
Innate immunity and metabolic stress drive a unique form of cell death
In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study…
Generative AI aids discovery of ISM3830’s novel scaffold
Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative…
New technique helps understand how bacterial shapes contribute to disease
Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean…
Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus
Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell…
New signaling molecule drives development of tissue resident memory T cells
We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the…
New clues in pancreas lymph nodes, spleen could help detect and prevent type 1 diabetes
Type 1 diabetes (T1D) impacts nearly two million Americans, and by the time most people learn they have…
Breakthrough in FcγRI inhibition opens path to safer autoimmune therapies
An international research group directed by UMC Utrecht have developed and characterized two first-in-class antibodies that specifically block…
Pediococcus acidilactici attenuates chronic stress-induced depression via generating metabolite indole-3-lactic acid and downregulating neuroinflammation | Journal of Neuroinflammation
Strain cultivation The Pediococcus acidilactici (strain GOLDGUT-EZMind), isolated from traditionally fermented sauerkraut originating from the Qinghai-Tibet Plateau in…
Study links common Epstein-Barr virus to autoimmune lupus
One of humanity’s most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic lupus…
Social media spreads both awareness and misinformation about allergies and asthma
From rare tick-borne meat allergy to everyday asthma, millions of people turn to social media for health advice.…