Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
How COVID mRNA vaccines may make cancer treatments more effective
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
CRATERs identified as key sites for T cell-mediated tumor destruction
Like the surface of the moon, new research published today in Cell finds the existence of craters on…
Scalable synthetic biology revolutionizes targeted therapy with logic-gate proteins
Targeted drug delivery is a powerful and promising area of medicine. Therapies that pinpoint the exact areas of…
Repeated sampling offers insight into glioblastoma therapy response
A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass…
Post-operative radiation therapy reduces pelvic relapse in high-risk bladder cancer
Radiation therapy could be an underused tool to reduce pelvic relapse risk for patients with locally advanced, muscle-invasive…
New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies
Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the…
Loss of Trp53 gene affects immune responses in ovarian cancer
A new research paper was published in Volume 16 of Oncotarget on September 22, 2025, titled “Loss of Trp53 results in…
Scientists Use Electricity To “Reprogram” the Immune System for Faster Healing
A Trinity College Dublin team has discovered that electrical stimulation can reprogram macrophages to suppress inflammation and accelerate…
New findings show lymph nodes educate T cells to combat disease
A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the…
Adjuvant chemo-immunotherapy may benefit patients with resected stage IB–IIIA NSCLC, trial suggests
Interim results from the NADIM ADJUVANT Phase III trial, led by the Spanish Lung Cancer Group (GECP), suggest…