Study explores racial differences in gastric cancer immunotherapy outcomes
Advanced gastric cancer remains one of the deadliest malignancies, with a 5-year overall survival rate below 10%. In…
New guidance aims to standardize tumor mutational burden in cancer
Immune checkpoint inhibitors have transformed cancer care, yet only a minority of patients respond to monotherapy, and immune-related…
Blood pressure drug boosts effectiveness of cancer therapy
In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP,…
Study revises the understanding of neutrophil dynamics during respiratory viral infection
Neutrophil infiltration is a hallmark of pulmonary inflammation during respiratory viral infections, yet the origin of these cells…
New nanoparticle therapy overcomes T cell exhaustion in solid tumors
Engineers at the University of Pennsylvania have developed a new type of lipid nanoparticle (LNP) that could one…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
Study finds cockroach allergy often driven by shared proteins across arthropods
A new molecular analysis reveals that many patients labeled as cockroach-allergic may actually be reacting to shared proteins…
Remote-controlled CAR T cells offer safer cancer therapy
Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells…
Preoperative combination treatment shows promise for some patients with pancreatic cancer
A new UCLA investigator-initiated study sponsored by the UCLA Health Jonsson Comprehensive Cancer Center has found that adding immunotherapy to…
Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
Rising lung cancer in never smokers demands urgent research focus
Lung cancer patients who have never smoked make up a significant and growing share of global lung cancer…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…