Study finds GLP-1 medicines cut fat while preserving muscle function
A new study in mice and humans suggests GLP-1 medicines drive weight loss primarily by reducing fat, while…
Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS…
“Bugs Delivering Drugs” – Researchers Publish New Approach To Colorectal Cancer Treatment Using Common Food-Borne Bacteria
Baylor University researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier…
Needle-thin brain implant enables recording and targeted drug delivery
A new type of brain implant may have implications for both brain research and future treatments of neurological…
Targeted fab fragments dismantle the allergy trigger
Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such…
Engineered extracellular vesicles enable antigen-specific regulatory T cell induction
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University…
New findings show why the human intestine uniquely presents gluten to T cells
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides…
Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells
By engineering nanomaterials that boost mitochondrial biogenesis, researchers show how stem cells can become powerful “mitochondrial biofactories,” offering…
Generative AI aids discovery of ISM3830’s novel scaffold
Casitas B-lineage lymphoma-b (CBLB) is an E3 ubiquitin–protein ligase that functions as an intracellular checkpoint and master negative…
Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory
By flipping a single genetic switch from APOE4 to APOE2 in adult mice, researchers reversed key Alzheimer’s-like changes…
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An…
Groundbreaking 3D dynamic cell co-culture models simulate MASLD progression
In a recent work published in BME Frontiers, a collaborative study by researchers from Griffith University, Queensland University…