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Browsing Tag

Kinase

17 posts
HHealth
Study: Bisphenol a exposure and major depressive disorder: an integrative analysis combining network toxicology, molecular docking, genetic epidemiology, and transcriptomic validation. Image Credit: monticello / Shutterstock
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How could bisphenol A raise depression risk? Study identifies six key molecular targets

  • April 1, 2026
Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may…
HHealth
Reversing age-related vision loss with retinal lipid therapy
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Retinal organoid study identifies pathways and compounds to protect cone cells

  • March 31, 2026
Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have…
HHealth
Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients
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Updated EULAR recommendations guide treatment decisions for rheumatoid arthritis

  • March 14, 2026
First published in 2010, the EULAR recommendations for the management of RA, the most frequent inflammatory rheumatic disease,…
HHealth
Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
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Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy

  • March 13, 2026
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS…
HHealth
NYU Langone strengthens world-leading GI cancer program with renowned leaders
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Unmasking the hyper-active circuitry of early Alzheimer’s

  • March 9, 2026
Neuroscientists at King’s College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer’s…
HHealth
Somatic genomics uncovers the outcomes of evolutionary competitions within our tissues, which can drive disease, counter monogenic disease, or protect from common diseases
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How somatic mutations shape disease and reveal new drug targets

  • March 9, 2026
Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets…
SScience
Second round of exercise boosts muscle growth in mice
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Identifying the core catalyst for muscle energy production

  • February 26, 2026
Researchers have investigated the role of a certain enzyme in regulating energy in muscle and exercise performance for…
TTechnology
Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia
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Tumor-targeted chimeric drug increases efficacy and limits side effects

  • February 8, 2026
Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more…
SScience
Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease
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Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease

  • January 27, 2026
From protein misfolding to gut–brain signalling, emerging evidence suggests that everyday plastic exposure may intersect with key biological…
HHealth
Study: Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control. Image Credit: Ahmet Misirligul / Shutterstock
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Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch

  • December 10, 2025
A microbial metabolite long linked to cardiovascular risk emerges as a surprising ally against metabolic inflammation, revealing how…
SScience
Evolutionary mutation in cGAS enhances naked mole-rat DNA repair
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New method reveals how human cells initiate DNA replication

  • December 3, 2025
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
SScience
AI toolset reveals links between lung fibrosis and aging
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Study reveals ATM kinase as the key driver of replicative senescence

  • December 2, 2025
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
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