Optibrium introduces graphical interface for QuanSA to enhance ligand-based affinity predictions
Optibrium, a leading developer of software and AI solutions for molecular design, today announced a new QuanSAâ„¢ plugin…
Protein targeted by cancer drugs may help the body fight influenza
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new…
Machine learning model predicts chemical reactions to accelerate drug discovery
Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly,…
Investigating microglia’s role in Alzheimer’s pathology
Announcing a new article publication for BIO Integration journal. Alzheimer’s disease (AD) is a neurodegenerative disorder and the…
Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
RNA micelles enable targeted chemotherapy without immune toxicity
A new study in mice hints at the potential to use tiny particles made with RNA molecules to…
Cryo-EM reveals NPFFR1 activation and guides novel ligand design
This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1…
New findings show why the human intestine uniquely presents gluten to T cells
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Immune cell dysregulation and inflammatory mediators shape epilepsy risk
Background and objectives Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal…
Integrating physicochemical laws into future AI models for better drug design
Proteins play a key role not only in the body, but also in medicine: they either serve as…
New fluorescent molecule could be used to generate clearer images of tumors
MIT chemists have designed a new type of fluorescent molecule that they hope could be used for applications…