Targeting lipid enzymes triggers starvation states in aggressive tumor cells
While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for…
Newly identified protein regulates lysosome positioning and cellular metabolism
Lysosomes are the control centers for the metabolism of cells and tissues, including the brain. They break down…
Tuberculosis bacteria stiffen cell membranes to evade immune destruction
Scientists have uncovered an elegant biophysical trick that tuberculosis-causing bacteria use to survive inside human cells, a discovery…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
Lysosomal activity in worms linked to transgenerational extension of lifespan
In the Wang Lab, it’s not unusual for worms to live for a long time. HHMI Janelia Research…