Pen-strep treatment rewires mechanical sensing in immune cells
Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to…
Dual-positive hybrid cells linked to shorter survival in advanced breast cancer
An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time…
TREM2 helps macrophages survive and repair radiation damaged skin
Recently, teams led by Prof. Yiming Zhang from Xinqiao Hospital, Army Medical University,Prof. Fazhi Qi from Zhongshan Hospital,…
Study identifies a promising strategy to treat brain metastases
A new study from researchers at Wake Forest University School of Medicine has identified a promising strategy to treat brain metastases, one of…
Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients
A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four…
Macrophage immune memory depends on lingering interferon gamma
Researchers from the University of California, Los Angeles, have discovered that immune cells known as macrophages remain poised…
IRF7 reshapes the behavior of vascular smooth muscle cells during atherosclerosis
Atherosclerosis underlies most heart attacks and strokes and is now recognized as a chronic inflammatory disease rather than…
Study shows DHPS enzyme controls macrophage maturation across multiple organs
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
Discovery of unexpected mechanism may help improve healing across muscle injuries
At the cellular level, the mechanics of how muscle tissue repair occurs gets complicated. There are significant differences…
How walnuts combat inflammation and oxidative stress in the body
From protecting brain cells to modulating immunity, walnut bioactives demonstrate remarkable antioxidant and anti-inflammatory potential; however, scientists caution…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…