Study reveals how inflammation disrupts lymph node structure in lymphoma
In aggressive lymphomas, inflammatory messengers reprogram the “conductors” of the immune system, causing lymph nodes structure to collapse.…
How somatic mutations shape disease and reveal new drug targets
Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets…
Jumping DNA fragments found to destabilize cancer genome
A study published today in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite,…
Customizable protein platforms offer new hope for cancer treatment
Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the…
Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the…
Bifunctional biomaterials for postoperative management of osteosarcoma
Background Osteosarcoma is the most prevalent primary malignant bone tumor in children and adolescents. The current standard treatment…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
Cleveland Clinic team uncovers genetic link to osteosarcoma
Researchers at Cleveland Clinic Children’s have helped identify a previously unknown gene that increases the risk of developing…
New algae gel provides realistic platform for breast cancer research
In 2020, right when Jane Baude was starting her Ph.D. research at UC Santa Barbara, she learned that…
Boosting the immune system to prevent cancer recurrence and improve survival
In experiments with mouse models of breast, pancreatic, and muscle cancers, researchers at Johns Hopkins All Children’s Hospital…