Mechanical force triggers metabolic changes that promote orthodontic bone formation
Bone adapts to mechanical force through coupled formation and resorption, a principle central to orthodontics. Periodontal ligament (PDL)…
Researchers uncover molecular pathway controlling bone resorption and tooth eruption
RUNX2 is best known as a master transcription factor of osteoblast differentiation. Mutations in, or haploinsufficiency of RUNX2…