The molecular mechanism that turns cool temps into nerve signals
When you reach into a bucket of ice, open your front door on a snowy day, or feel…
Detailed cell atlas reveals earliest changes in prostate cancer
Prostate cancer affects one in five Australian men, making it the most common cancer in the country. Now,…
Magnetic circular dichroism imaging of atomic-scale antiferromagnetic order at a buried interface
van der Laan, G. et al. Experimental proof of magnetic X-ray dichroism. Phys. Rev. B 34, 6529–6531 (1986).…
Pen-strep treatment rewires mechanical sensing in immune cells
Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to…
Disrupting protein production in tumors triggers potent immune responses
A new study led by Pierre Close’s team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how…
Mapping the evolution of AI in organelle segmentation
In organelle imaging, segmentation aims to accurately delineate pixels or voxels corresponding to target organelles from background, noise,…
Understanding PIEZO2 mutations and sensory disorders
Every time we feel a gentle tap on the skin, specialized nerve cells convert that physical force into…
Unmasking the hyper-active circuitry of early Alzheimer’s
Neuroscientists at King’s College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer’s…
New microscope captures 3D blood flow and oxygenation at single-cell resolution
The brain relies on real-time delivery of oxygen and nutrients through its microvasculature, which threads through neural tissue…
Protein partnership enhances innate immune sensing of viral RNA
Study reveals how two proteins cooperate in a key early step of antiviral detection, as reported by researchers…
Scientists reveal how the body senses cold and menthol
When you step outside on a winter morning or pop a mint into your mouth, a tiny molecular…
Multicolor electron microscopy reveals proteins and cell architecture at nanoscale resolution
Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the…