AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects
One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through…
Innate immunity and metabolic stress drive a unique form of cell death
In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study…
New method can stop or reverse the decline of cellular energy production
Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline…
“Living Fossil” Discovered by Accident Could Reshape Tree of Life
It’s not uncommon for a new species to be discovered among existing collections; it’s rare that the new…
Nanotech method loads stem cells with mitochondria to revive cells
Scientists at Texas A&M University say they may have found a way to stop or even reverse the…
Dysfunctional mitochondria shown to initiate the onset of Parkinson’s
For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson’s disease. But…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Study reveals acidic conditions as key to pancreatic cancer survival
Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful…
Exploring exercise’s physiological response to fight diabetes
Don’t love the gym? Neither does exercise scientist Ryan Montalvo. But he goes anyway. While any workout can…
Second round of exercise boosts muscle growth in mice
New research offers potential good news for those who’ve lapsed at the gym. The study found that mice…