Over-contracted gut muscles drive gastrointestinal symptoms in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in…
Neoantigens-loaded DC vaccines show strong potential to overcome tumor resistance
Despite the success of immune checkpoint inhibitors in revolutionizing oncology, their benefits remain limited to a small fraction…
Dysfunctional mitochondria shown to initiate the onset of Parkinson’s
For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson’s disease. But…
T cells drive vaccine effectiveness against porcine reproductive and respiratory syndrome virus
A new study shows that the effectiveness of current vaccines against porcine reproductive and respiratory syndrome virus (PRRSV)…
Study uncovers new mechanism for chromosome congression during mitosis
A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
BRCA2 gene family speaks out on inherited cancer and hope for the future
For women, the BRCA gene mutation dramatically increases the likelihood of getting breast or ovarian cancer, and a…
Orange Cats Are Genetically Unlike Any Other Mammal and Now We Know Why
Credit: Pixabay. Chris Kaelin, a geneticist at Stanford Medicine, found himself thinking about cats. Not just any cats,…
Pioneering personalized medicine by deciphering depression’s complex biological web
In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Najaf Amin unveils transformative insights that…
Discovery of CPD gene mutations sheds light on rare congenital hearing loss
Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing…