NSF grant supports UH researchers to investigate how mutation rates evolve across species
A nearly $1 million grant from the National Science Foundation will allow University of Houston researchers to investigate…
New genetic mutations linked to malaria drug resistance discovered
Researchers searching for genetic clues to the growing problem of malaria drug resistance identified new mutations associated with…
Scientists uncover how muscle actin filaments grow and renew themselves
Biophysicists unraveled a mystery of how muscles form at the molecular level and how they maintain their function.…
Study links inherited genetics to cancer susceptibility and progression
Scientists have found the first direct evidence of the powerful role our genetic makeup plays in influencing our…
Computationally designed antibody attacks previously untreatable KRAS cancer mutations
Antibodies are like “guided missiles” that find and attack cancer cells, but cancer-causing mutations inside cells have remained…
New BRAF protein conformation opens avenues for cancer treatment
Several types of cancer are triggered by mutations in a protein called BRAF. Researchers at the Paul Scherrer…
Myotonia may play a much larger role in driving muscle damage than previously recognized
For decades, researchers studying myotonic dystrophy type 1 (DM1) have focused on the disease’s underlying genetic cause: a…
Genetic research links KDF1 mutation to impaired dental epithelial organization
Dental enamel is the hardest substance in the human body, protecting teeth from wear, temperature changes, and decay.…
Family genetics study reveals clues to longer healthspan
Understanding why some people stay healthy without developing disease until late in life (have an increased healthspan), whereas…
New genetic driver found for rare small intestinal cancers
A signaling system known as the Wnt pathway plays a central role in how cells in the intestine…
Novel technology maps single-cell DNA-protein interactions
A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and…
Pleiotropic effects of cis-regulatory mutations
Wray, G. A. The evolutionary significance of cis-regulatory mutations. Nat. Rev. Genet. 8, 206–216 (2007). Article CAS PubMed …