Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
BRCA2 gene family speaks out on inherited cancer and hope for the future
For women, the BRCA gene mutation dramatically increases the likelihood of getting breast or ovarian cancer, and a…
Orange Cats Are Genetically Unlike Any Other Mammal and Now We Know Why
Credit: Pixabay. Chris Kaelin, a geneticist at Stanford Medicine, found himself thinking about cats. Not just any cats,…
Pioneering personalized medicine by deciphering depression’s complex biological web
In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Najaf Amin unveils transformative insights that…
Discovery of CPD gene mutations sheds light on rare congenital hearing loss
Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing…
Hotspots of human mutation point to clonal expansions in spermatogonia
Lawson, A. R. J. et al. Somatic mutation and selection at population scale. Nature https://doi.org/10.1038/s41586-025-09584-w (2025). Maeda, H.…
Refined DNA sequencing tool reveals hidden mutations behind aging and cancer
Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our…
Somatic mutation and selection at population scale
Cohort selection The TwinsUK study contains around 16,000 participants. From a preselection of 4,800 donors, we invited 1,796…
New T cell therapy targets CTNNB1 cancer mutation with promising results in animal studies
Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the…
Malaria-Transmitting Mosquito’s Genetic Diversity and Evolution Revealed
There are a variety of methods that have been established to curtail the spread of infectious disease, from…