Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory
By flipping a single genetic switch from APOE4 to APOE2 in adult mice, researchers reversed key Alzheimer’s-like changes…
I tried the Yōjō Vagus Nerve Stimulator — and it transformed my stress and sleep in two weeks
When’s the last time you gave your vagus nerve some attention? Thought so. If you’re au fait with…
Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment
Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy…
Exploring the gut-brain-immune axis in neurodegeneration
Neurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis…
Newly discovered perineural pathway enables HIV virus to redistribute throughout the body
Addressing the question of whether and how immune cells (macrophages) in the central nervous system (CNS) traffic out,…
New insight into TRPM3 heat sensor reveals how the body detects temperature
The ability to sense heat protects the body from burns and injury. But how the body actually feels…
New insights into how the blood-brain barrier safeguards the brain
By decoding the blood-brain barrier’s intricate structure and function, researchers are paving the way for new therapies that…
Discovery of CPD gene mutations sheds light on rare congenital hearing loss
Mutations in a gene known as CPD play a crucial role in a rare form of congenital hearing…
GLP-1 therapeutics may have the potential to treat alcohol and drug addiction
A popular class of therapies for treating diabetes and obesity may also have the potential to treat alcohol…
New drug candidates show promise for restoring myelin in MS
Multiple sclerosis, or MS, is a chronic autoimmune disease affecting more than 2.9 million people worldwide. It occurs when…
Repeated sampling offers insight into glioblastoma therapy response
A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass…
COMBINEDBrain and MUSC join forces to launch pediatric CNS biorepository
COMBINEDBrain, a leader in advancing translational neuroscience research, and the Medical University of South Carolina (MUSC), one of…