Neuron lattice structure may guard against neurodegeneration
Brain cells are constantly swallowing material from the fluid that surrounds them – signaling molecules, nutrients, even pieces of their own surfaces – in a process…
‘Partial reprogramming’ of engram neurons restores memory performance in mice
Age-related memory decline and neurodegenerative diseases like Alzheimer’s are often thought of as irreversible. But the brain is…
Minimally invasive biopsy enables real-time tracking of amyloid disease progression
Transthyretin amyloidosis (ATTR) is a rare, progressive and highly aggressive degenerative disease. It is caused by the misfolding…
Regular aerobic exercise slows a key marker of brain aging in midlife
A year of consistent aerobic activity didn’t just boost fitness; it shifted MRI-based brain age in early to…
MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils
One of the hallmarks of Alzheimer’s disease is the clumping of proteins called Tau, which form tangled fibrils…
Opposing protein forces fine tune mRNA stability in human cells
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders…
Discovery of smOOP RNAs reveals hidden rules of cellular phase separation
Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing…
Study reveals how aging reshapes protein chemistry in the brain
A study by the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena shows that the…
Preclinical study shows aged garlic extract improves memory and reduces anxiety
New findings show that aged garlic extract reshapes brain pathways tied to memory and emotion, revealing a promising…
Midlife blood test may reveal Alzheimer’s disease risk in advance
A simple blood test for platelet activity at middle age could one day help identify people at risk…
Exploring the gut-brain-immune axis in neurodegeneration
Neurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis…
Women with isolated REM sleep behavior disorder show lesser brain atrophy than men
A large international study involving nearly 700 participants reveals that women with a precursor condition to Parkinson’s disease…