Advances in chemistry and delivery are taking oligonucleotide medicines beyond rare diseases
Decades of work on RNA targeting, chemical modification, and tissue-specific delivery are reshaping what programmable genetic medicines can…
Silver nanoparticles enable precise DNA cutting and assembly
DNA is composed of long chains that act as the blueprint for living organisms. In genetic engineering, scientists…
Antisense oligonucleotides reverse rare neurodevelopmental disorder in preclinical models
Scientists at St. Jude Children’s Research Hospital have found they can reverse the effects of HNRNPH2-related neurodevelopmental disorder using…