Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Intraoperative radiation reduces the recurrence rate of pancreatic cancer
Using targeted radiation during surgery – referred to as intraoperative radiation – to eliminate pancreatic cancer cells that…
Global Virus Network announces the addition of three new Centers of Excellence
The Global Virus Network (GVN), a coalition of leading medical virologists representing 80+ Centers of Excellence and Affiliates…
Context-dependent impact of type I interferon signaling in cancer | Molecular Cancer
Hardy MP, Owczarek CM, Jermiin LS, Ejdebäck M, Hertzog PJ. Characterization of the type I interferon locus and…
Development and external validation of a FISH-clinical nomogram for predicting overall survival in bladder cancer patients after radical cystectomy | BMC Cancer
Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023;73(1):17–48. PubMed Google…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
The MyCancerGene study: a hybrid type 1 effectiveness-implementation randomized study comparing a patient-centered digital genetic health portal to usual care after receipt of cancer genetic testing | BMC Cancer
Robson ME, Storm CD, Weitzel J, Wollins DS, Offit K. American society of clinical oncology policy statement update:…
Association of genetic variants in m1A modification core genes and neuroblastoma risk | BMC Cancer
Park JR, Kreissman SG, London WB, Naranjo A, Cohn SL, Hogarty MD, et al. Effect of tandem autologous…
Curcumin in prostate cancer: a systematic review of molecular mechanisms and nanoformulated therapeutic strategies | BMC Cancer
Curcumin, a dietary polyphenol derived from Curcuma longa, has been extensively studied for its pleiotropic biological activities, particularly…
Reporter’s Notebook: The Overdue Breakout for Gene Therapy and Gene Editing
As gene editing enters a new era, leaders discuss Baby KJ’s implications for families, science, and industry. (Left…
Association between triglyceride-glucose index and pathological invasiveness of lung adenocarcinoma in patients with solitary ground-glass nodules: a cross-sectional study | BMC Cancer
In this retrospective analysis of 278 individuals with solitary pGGNs pathologically verified as lung adenocarcinoma following surgery, an…
Loneliness and isolation associated with higher death risk in cancer patients
Loneliness and social isolation are linked to a heightened risk of death from cancer as well as from…