A study links a blood protein to memory and brain changes in Down syndrome
A study combining blood samples, memory assessments, and brain scans examines whether a protein found at nerve cell…
Could the Mediterranean diet protect the brain through the gut?
From microbial metabolites to inflammation and the blood-brain barrier, researchers trace how Mediterranean eating could influence neurodegeneration, while…
Active form of meprin-β protein increases in people with Alzheimer’s disease
A team from the Altered Molecular Mechanism in Alzheimer’s Disease and Dementia laboratory, led by Javier Sáez Valero,…
BCLXL blockade rewires cell fate to overcome PARP inhibitor resistance in ovarian cancer
Kaufman, B. et al. Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation. J. Clin.…
Scientists discover metabolite fueling aggressive brain tumor growth
Virtually all high-grade, aggressive gliomas in adults accumulate massive amounts of a metabolite called guanidinoacetate (GAA) that overstimulates…
Scientists traced a hidden immune route that may worsen tau-linked brain damage
Researchers traced an immune pathway from brain-draining lymph nodes to tau-affected tissue, revealing how peripheral immune activity may…
Three Lotto players split $1m as Powerball rolls over to $28m
Powerball will be $28m for this Saturday’s draw after going unclaimed on Wednesday night. Three Lotto players have…
Faulty myelin-making brain cells may help drive cognitive decline with age
A rare combination of lifelong cognitive tracking, postmortem brain analysis, and targeted mouse experiments reveals unexpected changes in…
Shared protein pathology redefines treatment for multiple neurodegenerative diseases
On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem…
Lancet review examines possible amyloid-beta transmission through blood transfusions
A review and opinion piece published in The Lancet and led by UCL (University College London) and UCLH…
New genetic mutations linked to malaria drug resistance discovered
Researchers searching for genetic clues to the growing problem of malaria drug resistance identified new mutations associated with…
Alzheimer’s markers show crucial differences across diverse global populations
Established Alzheimer’s markers are also detected in blood samples from Nigeria and Tanzania. But other proteins in the…