Two new TB vaccines show safety but limited protection
Two new vaccines to prevent tuberculosis (TB) are safe for use in adults and children, but they do…
Evolocumab trial could reshape how doctors treat high-risk cholesterol patients
A major cholesterol guideline arrived just as pivotal new trial data emerged, revealing how fast-moving evidence could soon…
Oral semaglutide fails to slow early Alzheimer’s decline in two phase 3 trials
Despite hopes raised by earlier observational studies and biomarker shifts, The Lancet trials found that oral semaglutide did…
Psychiatrists’ use of biomarkers could open a new window into mental health diagnoses
Amanda Miller was 30 and pregnant with her second child in Hershey, Pennsylvania, when she developed depression. After…
Clinical trial tests a newer, targeted therapy for IDH mutant astrocytoma
A new clinical trial led by the Alliance for Clinical Trials in Oncology will investigate if a combination…
Low‑dose oral lithium may help slow the decline of verbal memory, trial suggests
Lithium-a decades-old treatment for bipolar disorder-may hold potential neuroprotective benefits beyond mood stabilization. An exploratory clinical trial from…
Meningococcal B vaccine fails to prevent gonorrhea, trial shows
Contrary to existing evidence from observational studies, the meningococcal B vaccine (4CMenB) has no effect on preventing the…
Combined GLP-1 and GLP-2 treatment appears safe but does not beat placebo for obesity
Can combining two gut hormone pathways unlock better obesity treatments? In the first human trial of dapiglutide, researchers…
Psychedelic effects of ketamine do not predict sobriety
The psychedelic effects recreational users often seek from taking ketamine do not predict the therapeutic benefits for people…
Magnesium lower fasting blood sugar in older adults
A carefully controlled trial finds that magnesium can lower fasting glucose in older adults with magnesium deficiency, but…
Novel neuroprotective drug improves recovery after acute ischemic stroke
Stroke patients treated intravenously with loberamisal, a novel neuroprotective medication, daily for 10 days and starting within 48…
Ashwagandha aids recovery without blunting training stress in athletes
A controlled trial in team-sport athletes suggests Ashwagandha may help maintain hormonal balance and support recovery and power…