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Browsing Tag

Preclinical

89 posts
HHealth
Study reveals a new oncogenic role of NBL1 in ovarian cancer metastasis
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Wistar scientists develop new bispecific T cell engager to target ovarian cancer

  • July 21, 2026
Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against…
HHealth
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
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New tumor organoids strengthen precision oncology research

  • July 21, 2026
Significant advances have been made in the development of patient-derived tumor “organoids” for preclinical research, in two new…
HHealth
Gut microbial metabolites may shape vulnerability to stress-related mental disorders
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Gut microbial metabolites may shape vulnerability to stress-related mental disorders

  • July 21, 2026
Jul 20 2026 From short-chain fatty acids to bile acids, researchers trace how microbial chemistry could influence brain…
HHealth
Study: Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment. Image Credit: Lightspring / Shutterstock
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Blood p-tau217 levels signal cognitive impairment risk years before symptoms emerge

  • July 17, 2026
A six-cohort analysis links higher baseline p-tau217 to rising 5- and 10-year risks, bringing presymptomatic risk models closer…
HHealth
First FDA-approved islet transplant at UI Health ends insulin dependence
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First clinical trial evaluates stem cell therapy for Huntington’s disease

  • July 9, 2026
An update on the first clinical trial evaluating a pluripotent stem cell-derived neural stem cell therapy for Huntington’s…
HHealth
‘Rogue’ DNA rings identified as drivers of aggressive brain cancer
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Experimental compound BA-101 overcomes chemotherapy resistance in glioblastoma

  • July 9, 2026
Scientists have identified a promising new strategy to tackle one of the biggest obstacles in treating glioblastoma, one…
HHealth
HIV protein Tat found to increase vulnerability to tuberculosis
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BCG vaccine may remodel the human brain’s immune environment

  • July 6, 2026
New research led by Mass General Brigham investigators suggests that the Bacillus Calmette-Guérin (BCG) vaccine – which is…
TTechnology
Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors
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Tailored drug combinations improve outcomes for treatment-resistant advanced melanoma

  • July 2, 2026
A new study led by researchers at The University of Texas MD Anderson Cancer Center has identified a way to tailor drug combinations based on specific…
SScience
‘Rogue’ DNA rings identified as drivers of aggressive brain cancer
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Study potential new therapeutic strategy for patients with ATRX-mutant gliomas

  • July 2, 2026
A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of…
HHealth
Review: Effects of cannabidiol on anxiety- and depressive-like behaviors and cognition: a systematic review and meta-analysis of preclinical studies. Image Credit: Creativan / Shutterstock
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Cannabidiol shows preclinical promise for anxiety, depression and cognition

  • July 2, 2026
A new Molecular Psychiatry meta-analysis suggests CBD may improve emotional behavior and cognition in animal models, but researchers…
HHealth
Mucus-inspired hydrogel improves healing in animal models of gastric injury
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AI-guided microneedle patch changes shape to heal chronic wounds

  • June 26, 2026
Chronic wounds remain a major healthcare challenge, especially for people with diabetes, who often experience delayed healing, persistent…
HHealth
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
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Engineered silica nanoparticles destroy prostate tumors in preclinical study

  • June 15, 2026
Prostate-targeted, engineered nanoparticles made of amorphous silica are effective in killing prostate tumors directly while enhancing anti-tumor immunity,…
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