Novel metal-free prodrug suppresses cancer spread in preclinical models
A carefully designed metal-free carbon monoxide prodrug may help prevent some of the deadliest forms of cancer from…
Scientists target NOX4 protein in skeletal muscle to combat aging
The powerful role of exercise in maintaining skeletal muscle could be the key to improving health and resilience…
A hidden immune pathway may help explain why Alzheimer’s inflammation persists
A newly identified epigenetic pathway reveals how overactive microglia may sustain brain inflammation in Alzheimer’s, suggesting KAT7 as…
Brain-targeted estrogen reduces breast cancer treatment side effects
Most breast cancers are worsened by estrogens. To combat the recurrence of these cancers, clinicians treat patients with inhibitors for estrogen…
Flu drugs may reduce cognitive decline in people with HIV
A class of flu drugs may reduce cognitive decline and premature aging in people living with chronic viral…
Scientists rethink GLP-1 delivery to improve dosing, tolerability, and adherence
From microneedles to nanocarriers, researchers are rethinking how GLP-1 medicines could become longer-lasting, easier to tolerate, and more…
Degrading mutant KRAS protein induces greater lung cancer regression
KRAS is one of the oncogenes most frequently altered in cancer, mutated in approximately one-third of lung adenocarcinomas.…
Virtual reality navigation deficits predict future brain volume loss
Alzheimer’s disease (AD) often begins long before it is clinically recognized, with subtle brain changes emerging years before…
Human telomerase shows limited function across different animal species
A new research paper was published in Volume 18 of Aging-US on April 13, 2026, titled “Cross species activity of TERT…
Scientists identify STING switch driving inflammation in Alzheimer’s disease
The brain has its own immune system, which detects threats and mounts a defense. A growing body of…
Antisense oligonucleotides reverse rare neurodevelopmental disorder in preclinical models
Scientists at St. Jude Children’s Research Hospital have found they can reverse the effects of HNRNPH2-related neurodevelopmental disorder using…
EV-RNAs show promise for IBD diagnosis and treatment
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive…