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Browsing Tag

Preclinical

90 posts
HHealth
Study: Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease. Image Credit: Andrii Vodolazhskyi / Shutterstock
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Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

  • February 12, 2026
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
TTechnology
University of Missouri launches first on-campus radiopharmaceutical clinical trial
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University of Missouri launches first on-campus radiopharmaceutical clinical trial

  • February 10, 2026
In a major leap for cancer care at the University of Missouri, the School of Medicine and MU…
TTechnology
Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia
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Tumor-targeted chimeric drug increases efficacy and limits side effects

  • February 8, 2026
Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more…
TTechnology
Nurse injecting insulin in diabetic girl belly. Close up of young girl with type 1 diabetes taking insulin with syringe needle.
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Immune scaffold predicts onset weeks early

  • February 4, 2026
A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before…
SScience
Blood-based biomarkers reveal barriers to diversity in Alzheimer’s disease trials
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Hippocampus reorganizes memories to anticipate future outcomes, study finds

  • January 30, 2026
A preclinical study published in Nature has found evidence that the hippocampus, the brain region that stores memory, also reorganizes…
SScience
Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease
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Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease

  • January 27, 2026
From protein misfolding to gut–brain signalling, emerging evidence suggests that everyday plastic exposure may intersect with key biological…
HHealth
New study exposes a targetable vulnerability in acute myeloid leukemia
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New study exposes a targetable vulnerability in acute myeloid leukemia

  • January 19, 2026
New research co-led by Indiana University School of Medicine scientists has exposed a vulnerability in acute myeloid leukemia…
TTechnology
Bowel preparation for colonoscopies may temporarily alter gut balance, preclinical study suggests
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Bowel preparation for colonoscopies may temporarily alter gut balance, preclinical study suggests

  • January 10, 2026
New preclinical research suggests that bowel preparation procedures for colonoscopies may temporarily alter gut balance, culminating in unappreciated…
HHealth
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
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Vitamin A derivative suppresses immune response and cancer vaccine efficacy

  • January 6, 2026
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by…
HHealth
New insights reveal persistent genome structure during cell division
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Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

  • December 30, 2025
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
HHealth
Regular mammograms linked to longer survival in women over 80
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Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

  • December 27, 2025
Dec 26 2025 A new study published today in Science Translational Medicine by researchers at The University of…
HHealth
Simple blood test maps hidden Alzheimer’s disease changes
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Simple blood test maps hidden Alzheimer’s disease changes

  • December 21, 2025
A large community study shows that Alzheimer’s-related brain changes are far more widespread with age than symptoms alone…
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