Molecular switch in neurons found to limit the regrowth of damaged axonal fibers
Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that…
Highly potent opioid shows potential as therapy for pain and opioid use disorder
Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential…
How could bisphenol A raise depression risk? Study identifies six key molecular targets
Researchers combined genetic epidemiology, transcriptomics, molecular docking, and mouse experiments to show how a common endocrine-disrupting chemical may…
Drugs targeting TIE2 protein could help prevent formation of cerebral cavernous malformations
Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor…
Circulating tumor DNA predicts breast cancer relapse after treatment
Fragments of tumor DNA circulating in the bloodstream of patients with breast cancer can predict whether they are…
New pathway enhances brown fat thermogenesis and metabolic health
Researchers have determined how a key protein activates brown fat by expanding blood vessels and nerves in the…
Study revises the understanding of neutrophil dynamics during respiratory viral infection
Neutrophil infiltration is a hallmark of pulmonary inflammation during respiratory viral infections, yet the origin of these cells…
GLP-1 drugs cut heart and kidney risks in type 1 diabetes study
A major real-world analysis suggests GLP-1 receptor agonists could offer heart, kidney, and weight benefits in type 1…
Do artificial sweeteners increase appetite or food intake?
Do artificial sweeteners really disrupt appetite and drive overeating, or could they help curb sweet cravings without increasing…
Study finds GLP-1 medicines cut fat while preserving muscle function
A new study in mice and humans suggests GLP-1 medicines drive weight loss primarily by reducing fat, while…
Patients who stop GLP-1 drugs often restart or try alternatives
A large real-world study shows that patients who stop popular GLP-1–based weight-loss drugs often return to treatment or…
Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS…