Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation
A novel nasal booster approach may help close the gap between systemic vaccination and infection-blocking mucosal immunity, offering…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
Transcription factor HOXD13 drives melanoma growth and immune evasion
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors’…
Review links betel nut addiction to cancer, heart disease, and metabolic risks
Widely used yet often underestimated, betel nut chewing poses significant health risks, and researchers continue to search for…
Bacteria repurpose viral injection systems to target diverse cells
New study shows how bacteria adapted a virus-derived injection system to recognize and attach to many different types…
Palbociclib improves progression-free survival in HER2 positive breast cancer
PrECOG, LLC, today announced the publication of final results from the pivotal phase 3 PATINA study in the…
Targeted fab fragments dismantle the allergy trigger
Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such…
Improving survival in people with severe psychiatric disorders
An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap…
Incretin-based diabetes drugs show potential protective effects against dementia
A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes,…
How bariatric surgery outperforms GLP-1 in body fat loss
A large real-world study reveals how surgery and GLP-1 therapies reshape fat and lean tissue differently over time,…
Vitamin A derivative suppresses immune response and cancer vaccine efficacy
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by…