New signaling pathway enhances blood stem cell transplantation outcomes
Gene therapies are used to treat many different blood disorders. However, blood stem cells often fail to achieve…
Disrupted circadian rhythms may influence tumor immunity and cancer spread
Epidemiological studies link light at night (LAN), shift work, chronic jet lag (CJL), and core clock gene mutations…
New BCR analysis method tracks immune recovery after stem cell transplantation
A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of…
COVID-19 immunity shows cross-reactivity against related bat coronaviruses
People who recovered from COVID-19 infection or were vaccinated against SARS-CoV-2 are more likely to have immunity to…
Research makes strong case for broader use of GLP1 drugs to protect hearts
New research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD)…
Study identifies shared pathway driving cardiac fibrosis
Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that…
GLP-1 drugs may influence chronic pain through gut-brain and immune pathways
From microbial metabolites and spinal microglia to osteoarthritis and headache trials, researchers map how GLP-1 signaling intersects with…
Discovery of receptor-free signaling reveals better targets for treating autoimmune diseases
Our understanding of how cells interact with each other has been driven for decades by the central concept…
City of Hope develops adaptive plug-and-play CAR T technology to attack tumors
Researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in…
Hedgehog coronaviruses reveal potential pathways for cross-species transmission
Washington State University researchers have discovered how a group of coronaviruses circulating in hedgehogs invades host cells, a…
Tirzepatide vs semaglutide for asthma: the difference was smaller than researchers expected
Researchers compared two widely used incretin therapies in more than 16,000 matched adults with asthma and type 2…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…