Researchers identify key barrier preventing self repair of heart cells
Specialized cells in our body make biological tradeoffs to do certain jobs. To support large and hardworking hearts…
New strategy combines cancer immunotherapy and gene therapy in a single nanoparticle
Cancer cells survive by hiding from the immune system’s surveillance. A KAIST research team has developed a new…
Lifestyle changes improve MASLD by suppressing key molecular pathway
A molecular explanation for how lifestyle interventions protect the liver Lifestyle modification is the cornerstone of managing metabolic…
Oral microbiome imbalances may contribute to symptomatic hand arthritis
Specific imbalances and disruptions to the oral microbiome have been linked to symptomatic hand arthritis by a study published…
New portable strip test accurately detects mosquito-borne viruses
A research team has developed a multisite bridging-mediated lateral flow immunoassay (mbLFIA) that enables highly sensitive, portable detection…
Targeting CMPK2-intervened redox metabolism to mitigate hepatic ischemia-reperfusion injury
HIRI is a major clinical challenge that occurs when blood supply to the liver is temporarily interrupted and…
Myotonia may play a much larger role in driving muscle damage than previously recognized
For decades, researchers studying myotonic dystrophy type 1 (DM1) have focused on the disease’s underlying genetic cause: a…
Engineered ribozyme repairs broken RNA to explain origins of life
In most modern cells, DNA stores the genetic blueprint, and relies on proteins to replicate, repair and build…
Scientists Catch a “Jumping Gene” Moving Between Species
Scientists have uncovered a possible new route by which “jumping genes” move between species. Credit: Shutterstock A jumping…
Targeted therapy doubles progression-free survival in rare bile duct cancer
Results of the ongoing eNRGy trial, a single-arm, multicenter, global phase 2 clinical trial evaluating zenocutuzumab in solid…
Evolutionary noncoding RNAs reveal new targets for cancer therapy
In cancer research, one person’s junk is increasingly becoming another person’s treasure. Scientists have now uncovered new evidence…
Scientists capture atomic images to improve RNA interference drug design
RNA interference is a natural mechanism for living cells to control whether specific genes are being used or…