Early genomic testing prevents years of inconclusive visits for pediatric patients
For many families, eight years of uncertainty meant repeated specialist visits, inconclusive genetic tests and the growing fear…
New gene target offers hope for fatal infant cardiomyopathy
Researchers from the Keck School of Medicine of USC have made an important advance toward understanding-and potentially treating-a rare cardiomyopathy…
How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
Understanding cell messaging provides a blueprint for targeting inaccessible tumors
Researchers at University College Dublin have discovered a previously unknown “courier system” that cells use to deliver coherent…
Rat hepatitis E virus may be a hidden cause of hepatitis in humans
A growing body of evidence suggests that rat hepatitis E virus is spilling into humans more often than…
EV-RNAs show promise for IBD diagnosis and treatment
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive…
Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…
Study identifies a common hidden genetic cause of neurodevelopmental disorder in children
A major genetic study has uncovered a surprisingly common recessive cause of neurodevelopmental disorder, revealing how hidden changes…
Genomic study advances prioritization of variants in cancer diagnostics
Hiroshima University researchers have developed a practical framework to identify candidate pathogenic variants hidden among the large number…
Study revises the understanding of neutrophil dynamics during respiratory viral infection
Neutrophil infiltration is a hallmark of pulmonary inflammation during respiratory viral infections, yet the origin of these cells…
Study reveals dual role of PFK enzyme in metabolism and cell cycle progression
A metabolic enzyme studied for over seven decades has a hidden second function – it can unwind RNA…
Researchers identify cellular drivers of gut scarring in Crohn’s disease
As inflamed regions of the gut form scar tissue, the space within the gut lumen becomes smaller and…