Advances in chemistry and delivery are taking oligonucleotide medicines beyond rare diseases
Decades of work on RNA targeting, chemical modification, and tissue-specific delivery are reshaping what programmable genetic medicines can…
Microscopic peptide droplets reduce colorectal tumor growth in mice
Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed microscopic peptide droplets that deliver large amounts of…
New strategy combines cancer immunotherapy and gene therapy in a single nanoparticle
Cancer cells survive by hiding from the immune system’s surveillance. A KAIST research team has developed a new…
Scientists capture atomic images to improve RNA interference drug design
RNA interference is a natural mechanism for living cells to control whether specific genes are being used or…
Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma
The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into…
New Bio-Implant for Spinal Cord Repair
Summary: Spinal cord injuries have long been considered permanent because neurons in the central nervous system lack the…
RNA micelles enable targeted chemotherapy without immune toxicity
A new study in mice hints at the potential to use tiny particles made with RNA molecules to…
What happens when microplastics reach the testes? Study shows autophagy and cell loss
Invisible plastic fragments from common tableware are turning up in semen; now, researchers reveal how nanoscale particles may…