New cord blood approach boosts survival in blood disease patients
A new way of using umbilical cord blood for treating blood diseases could make the treatment more accessible…
New mouse model reveals primary trigger of rare muscle disorder
Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and…
Engineered Stem Cells Become Lifelong Protein Factories
Researchers have genetically engineered blood stem cells to produce B cells that can churn out rare broad-action antibodies…
New nanoparticle system boosts scalable production of therapeutic exosomes
Researchers from Xi’an Jiaotong-Liverpool University (XJTLU) in China have developed a streamlined process that makes it easier to…
CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder
Ayrignac X, Carra-Dalliere C, Codjia P, Mouzat K, Castelnovo G, Ellie E, et al. Evaluation of CSF1R-related adult…
Scientists discover how muscle stem cells “flip a switch” to rebuild damaged muscle
Scientists at the University of California, Irvine’s School of Pharmacy & Pharmaceutical Sciences have discovered how muscle stem cells “flip…
Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
Alpha-Ketoglutarate Enhances Adipose-Derived Stem Cells Survival in Wound Healing by Hypoxia-Inducible Factor 1-Alpha-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics
BACKGROUND Adipose-derived stem cells (ADSCs) hold significant therapeutic potential for regenerative medicine, particularly in wound healing, owing to…
Genetic mismatch identified as major risk factor in cord blood transplantation
A Japanese study of more than 7,400 patients has identified a genetic mismatch that sharply increases the risk…
New brain discovery could help reverse the effects of aging
The promise of reclaiming youthful cognitive function has long been a holy grail for neuroscientists, but researchers may…
Stem cell implants aim to restore dopamine in Parkinson’s disease
Parkinson’s disease is a progressive neurodegenerative disorder that affects more than one million people in the United States,…
Engineered mesenchymal and endothelial cell layers effectively mimic native lymph nodes
The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal…