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Browsing Tag

Transcription factors

10 posts
SScience
Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
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Scientists discover master molecular switch for ginseng saponin production

  • July 24, 2026
Sanchi ginseng (Panax notoginseng) is a cornerstone of traditional Chinese medicine, prized for its saponins-bioactive compounds with anti-inflammatory,…
SScience
SLIT2 protein levels in the eye and blood linked to cognitive function
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Novel technology maps single-cell DNA-protein interactions

  • June 4, 2026
A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and…
SScience
Study: Mesenchymal drift: A convergent framework for the hallmarks of aging.  AI-generated biomedical illustration showing a transition from organized healthy tissue to fibrotic, inflamed tissue, representing mesenchymal drift during aging. Image Credit: ChatGPT / OpenAI.
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Mesenchymal drift may explain how aging cells lose their identity

  • June 1, 2026
A new review argues that aging may not be just a collection of molecular defects, but a progressive…
HHealth
Treating desmoplastic melanoma with immunotherapy before surgery can shrink or eliminate tumors
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New dual drugs eliminate tumors when combined with immunotherapy

  • April 2, 2026
Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of…
HHealth
Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
Read More

Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy

  • March 13, 2026
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS…
TTechnology
Transcription factor HOXD13 drives melanoma growth and immune evasion
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Transcription factor HOXD13 drives melanoma growth and immune evasion

  • February 11, 2026
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors’…
HHealth
New findings show why the human intestine uniquely presents gluten to T cells
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New findings show why the human intestine uniquely presents gluten to T cells

  • December 12, 2025
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides…
HHealth
New feedback mechanism in the brain could open avenues for treating people with sleep disorders
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Study explores how elevated growth hormone levels contribute to liver aging

  • November 18, 2025
A new research paper was published in Volume 17, Issue 10 of Aging-US on October 3, 2025, titled “Growth hormone excess…
SScience
Chlorinated compounds from slime mold show strong antibacterial activity
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Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway

  • October 30, 2025
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
SScience
Exploration of the GRAS family in Dimocarpus longan: identification, characterization, expression analysis and DlGRAS24 role in flowering time | BMC Plant Biology
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Exploration of the GRAS family in Dimocarpus longan: identification, characterization, expression analysis and DlGRAS24 role in flowering time | BMC Plant Biology

  • October 16, 2025
Identification of DlGRAS family genes In this study, 56 GRAS genes were identified in longan and named DlGRAS1–DlGRAS56…
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