New imaging method maps DNA replication forks with single-cell resolution
Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as…
High-resolution study maps molecular differences across six human cortical regions
A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in…
New dual drugs eliminate tumors when combined with immunotherapy
Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of…
Molecular switch in neurons found to limit the regrowth of damaged axonal fibers
Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that…
AlphaFold Database expands with millions of predicted protein complexes
A new collaboration between EMBL’s European Bioinformatics Institute (EMBL-EBI), Google DeepMind, NVIDIA, and Seoul National University has made…
Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS…
FOXJ1 gene may drive resistance to taxane chemotherapy in advanced prostate cancer
A gene called FOXJ1 may drive resistance to taxane chemotherapy during treatment for advanced prostate cancer, according to…
New insights into a hidden process that protects cells from harmful mutations | MIT News
Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or…
MSU scientists map the neural circuitry of drug compulsion
When a cocaine addict relapses, it isn’t a matter of personal failure – it’s the biological result of…
Study maps how NF-κB regulates gene expression in cells
To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department…
Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
Study reveals poxvirus’s unique DNA clamp for gene activation
A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study…