Study reveals how inflammation disrupts lymph node structure in lymphoma
In aggressive lymphomas, inflammatory messengers reprogram the “conductors” of the immune system, causing lymph nodes structure to collapse.…
Healthy thymus gland linked to longer life and immune stability
People with a healthy thymus gland live longer and are less likely to fall ill. In addition, immunotherapies…
Study links androgens to aggressive childhood brain tumor growth
An international team led by researchers at Baylor College of Medicine, Texas Children’s Hospital, McGill University and University…
New guidance aims to standardize tumor mutational burden in cancer
Immune checkpoint inhibitors have transformed cancer care, yet only a minority of patients respond to monotherapy, and immune-related…
Blood pressure drug boosts effectiveness of cancer therapy
In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP,…
Systematic review identifies stress-induced biological triggers in oncology
Stress is a constant companion in the oncologist’s office. It appears at the time of diagnosis, increases with…
Protein targeted by cancer drugs may help the body fight influenza
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new…
New nanoparticle therapy overcomes T cell exhaustion in solid tumors
Engineers at the University of Pennsylvania have developed a new type of lipid nanoparticle (LNP) that could one…
Newly identified protein regulates lysosome positioning and cellular metabolism
Lysosomes are the control centers for the metabolism of cells and tissues, including the brain. They break down…
Engineered bacteria may improve precision cancer drug delivery
Every year, millions of people are diagnosed with cancer globally; however, current treatments are limited by disease complexity.…
Clinical trial tests a newer, targeted therapy for IDH mutant astrocytoma
A new clinical trial led by the Alliance for Clinical Trials in Oncology will investigate if a combination…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…