Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy
Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS…
Scientists uncover unexpected cancer target on tumor cell surfaces
For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it…
Dual-positive hybrid cells linked to shorter survival in advanced breast cancer
An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time…
Targeting IGF2BP2 improves anti-angiogenic therapy effectiveness in colorectal cancer
A recent study published in Engineering has shed light on a novel therapeutic target for improving anti-angiogenic treatment…
FOXJ1 gene may drive resistance to taxane chemotherapy in advanced prostate cancer
A gene called FOXJ1 may drive resistance to taxane chemotherapy during treatment for advanced prostate cancer, according to…
“Bugs Delivering Drugs” – Researchers Publish New Approach To Colorectal Cancer Treatment Using Common Food-Borne Bacteria
Baylor University researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier…
Hormonal imbalance and gut microbes linked to cognitive deficits in patients with PitNETs
Pituitary neuroendocrine tumors (PitNETs) are commonly associated with visual disturbances and endocrine abnormalities; however, many patients also experience…
Scientists identify common molecular program across multiple brain tumor types
Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple…
MSK uncovers how interacting mutations shield breast cancer
Researchers at Memorial Sloan Kettering Cancer Center (MSK) have made an important discovery about how genetic mutations in breast…
Remote ischemic conditioning shields the heart from chemotherapy damage
Advances in cancer treatment mean that more people than ever are surviving the disease. However, some of the…
Study identifies a promising strategy to treat brain metastases
A new study from researchers at Wake Forest University School of Medicine has identified a promising strategy to treat brain metastases, one of…
Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients
A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four…