precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
Intraoperative radiation reduces the recurrence rate of pancreatic cancer
Using targeted radiation during surgery – referred to as intraoperative radiation – to eliminate pancreatic cancer cells that…
Two microbial metabolites compete to control the cells’ protein building machinery
The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
How COVID mRNA vaccines may make cancer treatments more effective
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
Researchers engineer a tool to dismantle cancer’s RNA-built growth hubs
In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of…
CRATERs identified as key sites for T cell-mediated tumor destruction
Like the surface of the moon, new research published today in Cell finds the existence of craters on…
Fatty acids found to be a primary driver of triple-negative tumor growth
A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast…
New approach protects the brain from radiation-induced cognitive decline
While tremendous relief comes from successfully battling cancer, survivors can also experience cognitive impairments caused by the disease…
Living near Superfund sites increases risk of aggressive breast cancer
Women living close to federally designated Superfund sites are more likely to develop aggressive breast cancers – including…