biopsy<\/a>-diagnosis of MCD had steeper eGFR declines compared with adult patients with MCD. MN patients aged 13\u201317 years and FSGS and IgA nephropathy\u00a0patients\u00a0aged\u00a018\u201344\u00a0years\u00a0at\u00a0the\u00a0time\u00a0of\u00a0biopsy\u00a0had\u00a0thesteepest\u00a0declines\u00a0in eGFR among their diagnosis cohorts. For patients with MCD, FSGS, and MN, no differences were detected among various age groups in the risk of progression to the composite outcome of death, kidney failure, or\u00a0\u226540% eGFR decline, while IgA nephropathy patients aged 6\u201312 years, 13\u201317 years, and 45\u201364 years had lower risks of progression compared with those aged 18\u201344 years.<\/p>\n
<\/p>\n
These findings suggest that young patients who obtained a kidney biopsy diagnosis of primary glomerular disease face significant risk of reaching kidney failure and requiring dialysis and \/ or a transplant in their lifetimes. We believe that future studies are needed to shed light on the lifetime burden and morbidity of primary glomerular diseases on patients diagnosed at a young age.”<\/p>\n
\n
<\/p>\n
Margaret Helmuth, MS, lead author\u00a0of the University of Michigan, Ann Arbor<\/p>\n
<\/p>\n
“Our research also highlights the importance of including children in clinical trials for disease treatment to mitigate against the adverse outcomes\u00a0they\u00a0face,”\u00a0added\u00a0co-author\u00a0Chia-shi\u00a0Wang,\u00a0MD,\u00a0MSc,\u00a0of\u00a0the\u00a0Emory\u00a0University School of Medicine.<\/p>\n
Study:\u00a0“Glomerular\u00a0Disease\u00a0Outcomes\u00a0Across\u00a0the\u00a0Lifespan:\u00a0Report\u00a0of\u00a0the\u00a0Cure Glomerulonephropathy (CureGN) Research Consortium”<\/p>\n
Source:<\/p>\n
American Society of Nephrology<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"New\u00a0research\u00a0reveals\u00a0that\u00a0contrary\u00a0toconventional belief, primary glomerular diseases are not necessarily benign for children and young adults. In fact, some subsets…\n","protected":false},"author":2,"featured_media":123913,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[15282,1061,86513,134,86514,2255,18162,51824,42819,111,139,69,1518],"class_list":{"0":"post-123912","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-biopsy","9":"tag-children","10":"tag-glomerulosclerosis","11":"tag-health","12":"tag-iga-nephropathy","13":"tag-kidney","14":"tag-kidney-failure","15":"tag-nephrology","16":"tag-nephropathy","17":"tag-new-zealand","18":"tag-newzealand","19":"tag-nz","20":"tag-research"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/123912","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=123912"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/123912\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/123913"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=123912"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=123912"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=123912"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}