{"id":181239,"date":"2025-12-13T02:58:07","date_gmt":"2025-12-13T02:58:07","guid":{"rendered":"https:\/\/www.newsbeep.com\/nz\/181239\/"},"modified":"2025-12-13T02:58:07","modified_gmt":"2025-12-13T02:58:07","slug":"lowering-blood-sugar-reduces-heart-risk-in-prediabetes","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/nz\/181239\/","title":{"rendered":"Lowering blood sugar reduces heart risk in prediabetes"},"content":{"rendered":"<p>Lowering blood sugar\u00a0levels\u00a0halves\u00a0the\u00a0likelihood of serious heart problems\u00a0in people with prediabetes.\u00a0<\/p>\n<p>According to King&#8217;s College London research, published\u00a0today\u00a0in The Lancet Diabetes\u00a0&amp;\u00a0Endocrinology,\u00a0bringing blood glucose back to normal levels \u2013 effectively reversing prediabetes \u2013 cuts\u00a0the risk of death from heart disease\u00a0or\u00a0hospital admission for heart failure by more than 50%.\u00a0<\/p>\n<p>This finding is especially important\u00a0in light of\u00a0recent research showing that lifestyle changes alone\u00a0&#8211;\u00a0including exercise, weight\u00a0loss\u00a0and dietary improvements\u00a0&#8211;\u00a0do not lower cardiovascular risk in people with prediabetes.\u00a0<\/p>\n<p>Together, these\u00a0discoveries\u00a0present\u00a0a new, life-saving target for prediabetes and the prevention of cardiovascular\u00a0disease,\u00a0while potentially signalling a paradigm change for the way these conditions are treated by clinicians.\u00a0<\/p>\n<p>&#8220;This study challenges one of the biggest assumptions in modern preventative medicine. For years, people with prediabetes have been told that losing weight, exercising more and eating healthier will protect them from heart attacks and early death. While these lifestyle changes are unquestionably valuable,\u00a0the evidence does not support\u00a0that\u00a0they\u00a0reduce\u00a0heart attacks or mortality in people with prediabetes. Instead, we\u00a0show that remission of prediabetes is associated with a clear reduction in fatal cardiac events, heart failure, and all-cause mortality.&#8221;\u00a0\u2013\u00a0Study lead author\u00a0Dr\u00a0Andreas\u00a0Birkenfeld,\u00a0Reader\u00a0in Diabetes, King&#8217;s College\u00a0London\u00a0and\u00a0University Hospital\u00a0Tuebingen\u00a0<\/p>\n<p>Prediabetes is a condition where blood\u00a0glucose\u00a0levels are higher than normal but not yet high enough to be <a href=\"https:\/\/www.news-medical.net\/health\/What-is-Type-2-Diabetes.aspx\" class=\"linked-term\" rel=\"nofollow noopener\" target=\"_blank\">diagnosed with type 2 diabetes<\/a>. While the condition\u00a0frequently\u00a0progresses to type 2 diabetes, it also carries risk of cardiovascular disease \u2013 one of the leading causes of death globally. In the UK, around one in five adults has diabetes or prediabetes. In the United States, that figure is more than one in three, and in China it rises to four in ten. Globally, more than one billion people are estimated to have prediabetes.\u00a0<\/p>\n<p>Led by\u00a0Dr\u00a0Andreas Birkenfeld\u00a0from King&#8217;s College London\u00a0and\u00a0University Hospital\u00a0Tuebingen, the study reanalysed data from two landmark diabetes prevention trials &#8211; the US Diabetes Prevention Program Outcomes Study (DPPOS) and the Chinese\u00a0DaQing\u00a0Diabetes Prevention Outcomes Study (DaQingDPOS).\u00a0Both are longitudinal studies, following participants with prediabetes over\u00a0several\u00a0decades, with interventions including increasing exercise and eating a healthy diet.\u00a0<\/p>\n<p>People who had\u00a0achieved\u00a0remission from prediabetes had a 58%\u00a0lower risk of cardiovascular death or hospitalisation\u00a0from heart failure. This effect persisted decades after normalising\u00a0glucose\u00a0levels, suggesting\u00a0a\u00a0lasting impact from regulating blood glucose.\u00a0<\/p>\n<p>The researchers also found that risk of heart\u00a0attack, stroke and other major adverse cardiovascular events were reduced by 42% in those who had\u00a0achieved\u00a0prediabetes remission.\u00a0<\/p>\n<p>The results were similar across both the Chinese\u00a0and US data.\u00a0<\/p>\n<p>Previous\u00a0analysis on\u00a0the studies had shown combined lifestyle interventions, including increased exercise and\u00a0eating a healthy diet,\u00a0did not\u00a0reduce\u00a0cardiovascular disease. This suggests that delaying diabetes onset alone does not\u00a0guarantee cardiovascular protection unless important metabolic changes occur.\u00a0<\/p>\n<p>&#8220;The study findings mean that prediabetes remission could\u00a0establish\u00a0itself &#8211; alongside lowering blood pressure, cutting cholesterol and stopping smoking \u2013 as a fourth major primary prevention tool that truly prevents heart attacks and deaths.&#8221;\u00a0added\u00a0Dr\u00a0Birkenfeld.\u00a0<\/p>\n<p>The research\u00a0is part of a longstanding collaboration between King&#8217;s College London\u00a0and\u00a0TUD Dresden University of Technology, known as the\u00a0transCampus.\u00a0<\/p>\n<p>&#8220;The\u00a0transCampus\u00a0is a unique partnership\u00a0established\u00a0by King&#8217;s College London and\u00a0the\u00a0TUD Dresden University of Technology\u00a0as a transnational strategic partnership based on the idea of true cooperation and an intense dedication for collaboration in\u00a0all fields. Guided by shared ideas, values and a devotion to research and education,\u00a0transCampus\u00a0enables researchers to work together beyond the means of a traditional partnership by sharing resources, combining their strength, and promoting transnational projects and knowledge transfer.&#8221;\u00a0&#8211; Professor Stefan Bornstein, Dean of\u00a0transCampus\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"Lowering blood sugar\u00a0levels\u00a0halves\u00a0the\u00a0likelihood of serious heart problems\u00a0in people with prediabetes.\u00a0 According to King&#8217;s College London research, published\u00a0today\u00a0in The&hellip;\n","protected":false},"author":2,"featured_media":117555,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[4250,4251,6294,3535,3619,3534,3248,4252,134,2862,5457,8148,2241,4367,111,139,69,18395,1518,145,13265],"class_list":{"0":"post-181239","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-blood","9":"tag-blood-sugar","10":"tag-cardiovascular-disease","11":"tag-diabetes","12":"tag-diet","13":"tag-endocrinology","14":"tag-exercise","15":"tag-glucose","16":"tag-health","17":"tag-heart","18":"tag-heart-disease","19":"tag-heart-failure","20":"tag-hospital","21":"tag-mortality","22":"tag-new-zealand","23":"tag-newzealand","24":"tag-nz","25":"tag-prediabetes","26":"tag-research","27":"tag-technology","28":"tag-type-2-diabetes"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/181239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=181239"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/181239\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/117555"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=181239"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=181239"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=181239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}