Researchers evaluated 140 healthy aging adults who received either a placebo, 500 mg of NR, 1,000 mg of BluNADBooster alone, or a blend of 500 mg of BluNADBooster and 500 mg of NR.<\/p>\n
![\"Healthy](\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2025\/12\/13783bd6-01be-43f5-bac3-26c0412af9d8AdobeStock_1668028002.jpeg\")
They found that BluNADBooster alone increased blood NAD+ levels by 26.48% and outperformed NR, which recorded a 22.69% increase.They found that BluNADBooster alone increased blood NAD+ levels by 26.48% and outperformed NR, which recorded a 22.69% increase. Meanwhile, the combination of both produced the largest rise (31.76%), highlighting their synergies.<\/p>\n
Overall, the research supports BluNADBooster as a cellular energy and longevity supplement for adults seeking proactive natural NAD+ support.<\/p>\n
Key findings for inflammation and cognitio<\/p>\n
BluNADBooster also inhibited CD38, a multifunctional protein on cell surfaces that drives NAD+ depletion when its levels are elevated along the aging process. As a result, BluNADBooster reduced enzymatic activity by 17.98%, according to the researchers.<\/p>\n
\u201cThis preservation of intracellular NAD+ pools supports healthier energy balance, more efficient metabolic signaling, and broader longevity pathways,\u201d they note.<\/p>\n
Through its rich polyphenol profile, BluNADBooster offered anti-inflammatory support, lowering key biomarkers associated with systemic inflammation and \u201cinflammaging,\u201d including TNF-\u03b1, IL-6, and GDF-15.<\/p>\n
In addition to its metabolic and inflammatory benefits, BluNADBooster also delivered cognitive support for healthy aging. Participants experienced significant improvements in cognitive performance, measured by the Mini-Mental State Evaluation system.<\/p>\n
BluNADBooster also contributed to improved physical endurance and energy, with the combination group showing a 9.94% increase in distance during the six-minute walk test.<\/p>\n
\u201cHealth-related quality of life scores were significantly greater in all groups after 60 days, with the combination therapy of BluNADBooster and NR having the greatest improvements in energy\/fatigue, daily living, bodily pain, emotional well-being, social functioning, and general health,\u201d NXT USA reports.<\/p>\n
Greenlight for NMN<\/p>\n
This week, botanical nutraceutical producers under the Natural Products Association (NPA) hailed a \u201csignificant victory\u201d for the dietary supplement industry as the US FDA confirmed this month that the NAD+ precursor NMN can be marketed as a dietary supplement, reversing a 2022 determination.<\/p>\n
\u201cThis is a significant development as it follows actions taken by the FDA in September, when the agency reversed its previous determination that the investigation of NMN as a drug precluded its use in supplements. FDA\u2019s determination came in response to an amended citizen petition and a lawsuit against FDA brought by NPA,\u201d states the NPA.<\/p>\n
\u201cFDA\u2019s recent letters \u2014 including its response to our amended citizen petition \u2014 represent a massive U-turn, and we\u2019re proud that we were able to help shape the outcome. NPA strongly objected when FDA made the wrong decision on NMN three years ago, and we fought it in the regulatory arena, in conversations with congressional offices, and ultimately in the courts,\u201d says Daniel Fabricant, Ph.D., president and CEO of NPA.<\/p>\n
Following the FDA\u2019s response to NPA\u2019s citizen petition in September, which resolved the NMN controversy, the association filed a notice to voluntarily dismiss (without prejudice) its lawsuit against the FDA in the Federal District Court.<\/p>\n
\u201cWhile others sat on the sidelines, NPA\u2019s efforts delivered an unequivocal victory on this specific issue,\u201d Fabricant adds. \u201cFurthermore, because of our actions, the FDA has now provided extremely valuable and additional clarity on the drug preclusion clause in the Dietary Supplement Health and Education Act of 1994, so this is, in a sense, a two-fer.\u201d<\/p>\n
\u201cNPA will use this opening to advance a legislative solution to the drug preclusion clause, which has been inconsistently interpreted and applied in ways that threaten lawful supplement ingredients long after they have been safely marketed to consumers.\u201d<\/p>\n
NPA\u2019s successful efforts to legitimize NMN<\/a> required \u201cextraordinary investments,\u201d including the filing of a formal citizen petition and subsequent litigation against the FDA<\/a>, notes Fabricant.<\/p>\n \u201cAbsent congressional action, the same uncertainty now looms over peptides and other next-generation ingredients that may become entangled in investigational new drug applications, chilling research, deterring investment, undermining innovation, and limiting consumer choice,\u201d he cautions.<\/p>\n \u201cRegulatory clarity is essential to ensure that DSHEA continues to function as Congress intended by providing a predictable, science-based framework that protects consumers while allowing innovation to flourish.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"New clinical science supports NXT USA\u2019s claims that its patent-pending herbal blend, BluNADBooster, outperforms a popular NAD+ precursor,…\n","protected":false},"author":2,"featured_media":186092,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36],"tags":[117298,134,72564,111,139,103590,44461,117299,556,117297,69],"class_list":{"0":"post-186091","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nutrition","8":"tag-blunadbooster","9":"tag-health","10":"tag-nad","11":"tag-new-zealand","12":"tag-newzealand","13":"tag-nicotinamide-riboside","14":"tag-nmn","15":"tag-nr","16":"tag-nutrition","17":"tag-nxt-usa","18":"tag-nz"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/186091","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=186091"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/186091\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/186092"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=186091"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=186091"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=186091"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}