{"id":291673,"date":"2026-02-19T12:45:09","date_gmt":"2026-02-19T12:45:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/nz\/291673\/"},"modified":"2026-02-19T12:45:09","modified_gmt":"2026-02-19T12:45:09","slug":"what-to-know-about-the-link-between-tattoo-ink-and-cancer-risk","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/nz\/291673\/","title":{"rendered":"What to know about the link between tattoo ink and cancer risk"},"content":{"rendered":"<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">\u201cPeople should not panic but they should better understand the nature of tattoo ink and the types of heavy metals and other carcinogens in those inks,\u201d says Christopher Bunick, an associate professor of dermatology at the Yale School of Medicine.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Whether you already have a tattoo or are thinking of getting one, here&#8217;s what scientists are learning about the long-term effects tattoo ink can have on the immune system, whether the size of a tattoo matters\u2014and why getting one removed isn\u2019t the answer.<\/p>\n<p>Mysterious mechanisms behind the link<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">Experts don\u2019t fully understand the underlying mechanisms linking tattoos to an elevated cancer risk, but there are several widely accepted theories about what may be going on.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">For one thing, even though tattoos appear on the skin, they are more than skin deep. When ink is injected deep into the skin, over time tiny particles can travel <a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/www.nature.com\/articles\/s41598-017-11721-z\" target=\"_blank\" dir=\"ltr\" rel=\"nofollow noopener\">through the lymphatic system and end up in the lymph nodes<\/a>; this can lead to hidden inflammation.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">\u201cYour body recognizes the ink as foreign substances and activates the immune system to try to remove it,\u201d explains Christel Nielsen, coauthor of the Lancet study and a researcher in the division of occupational and environmental medicine at Lund University in Sweden.\u00a0<\/p>\n<p><img decoding=\"async\" alt=\"A colorized scanning electron microscopic view of skin where a puncture hole is visible, left behind by a tattoo needle\" class=\"hsDdd NDJZt sJeUN IJwXl bmjsw TmzDJ DXqUA UMBA UbGlr \" data-testid=\"prism-image\" draggable=\"false\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/02\/C0570999-Tattoo_needle_puncture_in_skin_SEM.jpg\"\/><\/p>\n<p>This image is a colored scanning electron micrograph of the hole created by tattoo needle in the epidermis, or top layer, or human skin. To make tattoos permanent, tiny needles are used to punch through the top layer of the skin and into the next layer (dermis). <\/p>\n<p>Anne E. Weston, Science Photo Library<\/p>\n<p><img decoding=\"async\" alt=\"A microscopic cross section of skin, with a visible deposit of black ink beneath the outer layers of skin\" class=\"hsDdd NDJZt sJeUN IJwXl bmjsw TmzDJ DXqUA UMBA UbGlr \" data-testid=\"prism-image\" draggable=\"false\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/02\/C0176000-Skin_with_Tattoo_LM.jpg\"\/><\/p>\n<p>Unlike the epidermis (purple), the dermal layer (pink) of the skin is not shed when skin is tattooed. The injection of the pigment (black) triggers an immune response that results in the pigment becoming trapped inside fibroblast cells (light purple). This is what makes a tattoo permanent\u2014and may also be why tattoos are linked to immune system changes.<\/p>\n<p>Michael Abbey, Science Photo Library<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">In a\u00a0<a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2510392122\" target=\"_blank\" dir=\"ltr\" rel=\"nofollow noopener\">study in a November 2025 issue of\u00a0PNAS<\/a>, researchers gave mice tattoos on their footpads, using black, red, and green ink, then monitored how the ink was transported by the lymphatic system and accumulated in lymph nodes. They found that the ink is retained in certain immune cells called phagocytes within lymph nodes, and the phagocytes die and trigger a long-term inflammatory response. What\u2019s more, when the mice were given two different types of vaccines (for COVID-19 and influenza), the tattoo ink at the vaccine injection site altered the immune response to the vaccines.\u00a0<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">There are other factors at play. For one thing, tattoo inks contain various chemicals and some of these may be\u00a0<a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35592919\/\" target=\"_blank\" dir=\"ltr\" rel=\"nofollow noopener\">carcinogenic<\/a>, meaning they\u2019re linked to causing or increasing the risk of cancer. For example, black inks may contain chemicals called polycyclic aromatic hydrocarbons, which \u00a0may increase cancer risk, and red ink may contain azo dyes that can break down into compounds that may cause cancer under UV light exposure, says Matthew Cortese, a lymphoma specialist at the Roswell Park Comprehensive Cancer Center in Buffalo, New York.<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">(<a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/www.nationalgeographic.com\/health\/article\/gut-toxins-colon-cancer-early-diagnosis\" target=\"_blank\" dir=\"ltr\" rel=\"nofollow noopener\">Colon cancer is rising in young people. Finally, scientists have a clue about why<\/a>.)<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">In addition, some tattoo inks may contain heavy metals\u2014such as lead, cadmium, mercury, and others\u2014that are known to be toxic, as well as solvents and other additives like formaldehyde\u00a0and phenol, which are associated with allergic reactions, notes Kelly Johnson-Arbor, a physician and toxicologist at MedStar Georgetown University Hospital in Washington, D.C. \u201c\u00a0<\/p>\n<p class=\"EkqkG IGXmU nlgHS yuUao lqtkC TjIXL aGjvy \">\u201cThis deposition of ink and metals triggers three responses that are well-recognized risk factors for cancer\u2014chronic immune [system] activation, oxidative stress, and abnormal growth of white blood cells called lymphocytes,\u201d says Joe K. Tung, medical director of Falk Dermatology at the University of Pittsburgh Medical Center. <a class=\"zZygg UbGlr iFzkS qdXbA WCDhQ DbOXS tqUtK GpWVU iJYzE \" data-testid=\"prism-linkbase\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5551541\/\" target=\"_blank\" dir=\"ltr\" rel=\"nofollow noopener\">Oxidative stress<\/a>, which may be triggered by introducing foreign substances into the skin from tattoo ink, can damage tissue and increase cancer risk; by contrast, when lymphocytes grow in an uncontrolled way, they can turn into cancerous cells and tumors can form.\u00a0\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"\u201cPeople should not panic but they should better understand the nature of tattoo ink and the types of&hellip;\n","protected":false},"author":2,"featured_media":291674,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[161588,128692,134,22349,111,139,69,29476,50604,81448,81449],"class_list":{"0":"post-291673","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-can-tattoos-cause-cancer","9":"tag-do-tattoos-cause-cancer","10":"tag-health","11":"tag-lymphoma","12":"tag-new-zealand","13":"tag-newzealand","14":"tag-nz","15":"tag-skin-cancer","16":"tag-tattoo","17":"tag-tattoo-removal","18":"tag-tattoos"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/291673","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=291673"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/291673\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/291674"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=291673"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=291673"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=291673"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}