{"id":435143,"date":"2026-05-19T14:50:11","date_gmt":"2026-05-19T14:50:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/nz\/435143\/"},"modified":"2026-05-19T14:50:11","modified_gmt":"2026-05-19T14:50:11","slug":"colossal-biosciences-says-breakthrough-means-its-a-step-closer-to-resurrecting-giant-moa","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/nz\/435143\/","title":{"rendered":"Colossal Biosciences says breakthrough means it&#8217;s a step closer to resurrecting giant moa"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/05\/4JOD2PZ_EmbryoDevelopment_tif.jpeg\" width=\"1050\" height=\"590\" alt=\"Embryo development.\"\/><\/p>\n<p class=\"photo-captioned__information\">\nEmbryo development.<br \/>\nPhoto: Supplied \/ Colossal Biosciences\n<\/p>\n<p>A multibillion-dollar <a href=\"https:\/\/www.rnz.co.nz\/news\/on-the-inside\/566642\/first-the-dire-wolf-now-nz-s-giant-moa-why-real-de-extinction-is-unlikely-to-fly\" rel=\"nofollow noopener\" target=\"_blank\">de-extinction company<\/a> believes it is one step closer to resurrecting New Zealand&#8217;s largest and long-extinct flightless bird.<\/p>\n<p>Colossal Biosciences &#8211; headquartered in Texas &#8211; is heralding a &#8220;major breakthrough&#8221; in its development of an artificial egg that it says is crucial to giant moa &#8211; which died out around 500 years ago &#8211; once again walking the earth.<\/p>\n<p>The company said it had successfully hatched 26 chickens from a novel artificial egg, designed to be reproduced at scale and at any size.<\/p>\n<p>The biotech company, which recently <a href=\"https:\/\/www.rnz.co.nz\/news\/world\/557551\/scientists-say-they-have-resurrected-the-dire-wolf\" rel=\"nofollow noopener\" target=\"_blank\">claimed to have resurrected the &#8216;dire wolf&#8217;<\/a>, has <a href=\"https:\/\/www.newscientist.com\/article\/2481409-colossal-scientist-now-admits-they-havent-really-made-dire-wolves\/#:~:text=The%20dire%20wolf%20is%20%E2%80%9Cthe,with%20a%20few%20gene%20edits\" rel=\"nofollow noopener\" target=\"_blank\">courted controversy<\/a> with its de-extinction projects, with critics questioning the <a href=\"https:\/\/www.rnz.co.nz\/news\/national\/566386\/sir-peter-jackson-backs-project-to-de-extinct-moa-experts-cast-doubt\" rel=\"nofollow noopener\" target=\"_blank\">ethics of de-extinction<\/a> and whether it is even a valid claim.<\/p>\n<p>Although its South Island giant moa project faced some backlash when it was announced almost a year ago, it has <a href=\"https:\/\/colossal.com\/moa\/\" rel=\"nofollow noopener\" target=\"_blank\">financial backing<\/a> from filmmaker Sir Peter Jackson and is <a href=\"https:\/\/www.rnz.co.nz\/news\/national\/561131\/return-of-the-huia-why-maori-worldviews-must-be-part-of-the-de-extinction-debate\" rel=\"nofollow noopener\" target=\"_blank\">run in partnership with Ng\u0101i Tahu Research Centre<\/a> and Canterbury Museum.<\/p>\n<p>Colossal&#8217;s Australia-based chief biology officer, Andrew Pask, is convinced a lack of understanding is the main thing standing in the way of public support and said while the company&#8217;s core goal is to restore species, it also wants to use its technology to prevent further extinctions.<\/p>\n<p>Speaking to RNZ, Pask &#8211; who is also a professor at the University of Melbourne &#8211; said the company&#8217;s latest technological development was a significant step in solving the chicken and egg conundrum inherent in the moa project.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/05\/4JOD2PZ_Andrew_Pask_jpg.jpeg\" width=\"1050\" height=\"1575\" alt=\"Colossal Biosciences Australia-based chief biology officer, Andrew Pask.\"\/><\/p>\n<p class=\"photo-captioned__information\">\nColossal Biosciences Australia-based chief biology officer, Andrew Pask.<br \/>\nPhoto: Supplied \/ Colossal Biosciences\n<\/p>\n<p>Pask said the company is currently sequencing the moa genome (based on bone DNA) and hopes to find it only differs by a few percentage points from the genome of its closest living relatives, emu and the South American tinamou.<\/p>\n<p>After that, he said a living relative&#8217;s cells &#8211; the best candidate &#8211; could be genetically edited with moa-specific genes.<\/p>\n<p>&#8220;Once we have that, the cell needs to be turned back into a living bird and for that, there&#8217;s currently no surrogate bird species that lays an egg big enough, so we had to make the Colossal artificial egg.&#8221;<\/p>\n<p>He said the egg&#8217;s silicone-based membrane &#8211; a 3D-printed lattice shell &#8211; allowed oxygen to diffuse inside, overcoming a major design hurdle since first attempts in the 1980s.<\/p>\n<p>Pask said previous artificial eggs required high levels of oxygen to be piped in, causing damage to the DNA and long-term health of the growing chick.<\/p>\n<p>&#8220;So we had to engineer the artificial egg, really from the ground up again.<\/p>\n<p>&#8220;We wanted to make it as close as possible to development inside the natural egg, because we want to be able to hatch birds that are going to have a normal lifespan, normal reproductive capacity, so that we can use this for conservation purposes as well as recreating the moa &#8211; so we need to be able to recreate that really large egg.&#8221;<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/05\/4JOD1R0_Device_pdf.jpeg\" width=\"1050\" height=\"811\" alt=\"Colossal Biosciences is describing its artificial egg as a \" major=\"\" breakthrough=\"\" in=\"\" its=\"\" de-extinction=\"\" moa=\"\" project.=\"\"\/><\/p>\n<p class=\"photo-captioned__information\">\nColossal Biosciences is describing its artificial egg as a &#8220;major breakthrough&#8221; in its de-extinction moa project.<br \/>\nPhoto: Supplied \/ Christopher Klee (Colossal Biosciences)\n<\/p>\n<p>The egg could be used in a standard incubator, and in addition to good gas-exchange across the egg&#8217;s &#8216;shell&#8217; the transparent design also enabled scientists &#8211; for the first time &#8211; to monitor the chick&#8217;s development in real-time, Pask said.<\/p>\n<p>&#8220;All of those [developments] have been major, major breakthroughs.&#8221;<\/p>\n<p>Pask said the project is on hold while they study the 26 chickens that have been hatched from the novel egg and provided they&#8217;re healthy with normal lifespans, the egg would then be &#8220;scaled up&#8221; to emu size.<\/p>\n<p>The moa, however, was at least eight times larger in volume than an emu egg, he said.<\/p>\n<p>&#8220;It&#8217;s an enormous egg, so to do that we&#8217;d have to have our initial moa &#8230; conceived inside an emu egg and then we&#8217;d take that emu egg and put it [the embryo] into a large artificial egg which would be moa sized &#8230; add extra yolk, extra albumen [egg white] &#8230; to increase the volume of those components, so that it can then sustain the growth of a much larger chick, which is going to be our baby moa.&#8221;<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/05\/4JOD1TE_hatch_pdf.jpeg\" width=\"1050\" height=\"811\" alt=\"Colossal Biosciences says 26 chickens have been hatched from its novel artificial egg.\"\/><\/p>\n<p class=\"photo-captioned__information\">\nColossal Biosciences says 26 chickens have been hatched from its novel artificial egg.<br \/>\nPhoto: Supplied \/ Christopher Klee (Colossal Biosciences)\n<\/p>\n<p>Pask said it was hard to say when that would happen, but &#8220;less than 10 years, I&#8217;d say &#8211; if you want a ballpark&#8221;.<\/p>\n<p>In addition to the moa project, he hoped the artificial egg would act as a surrogate for critically endangered species &#8211; big or small.<\/p>\n<p>&#8220;So bird species that are really struggling with reproduction or really struggling [to breed] easily in captivity &#8211; this could be an absolute game-changer for us, being able to create a lot of a particular species of bird that we&#8217;d be able to release back into the wild and really help to boost population numbers.&#8221;<\/p>\n<p>He said the artificial egg also gave them a platform for early &#8220;genetic manipulations&#8221; on birds, possibly engineering them to be more resilient to disease or climate change.<\/p>\n<p>In New Zealand, he said that could mean introducing genetic variation to species that had tiny populations.<\/p>\n<p>&#8220;We can actually go back and sequence the DNA from animals that lived 50, 100, 150 years ago, have a look at the population diversity that they used to have and engineer that back in again, so you have really healthy breeding populations.&#8221;<\/p>\n<p><a href=\"https:\/\/radionz.us6.list-manage.com\/subscribe?u=211a938dcf3e634ba2427dde9&amp;id=b3d362e693\" rel=\"nofollow noopener\" target=\"_blank\">Sign up for Ng\u0101 Pitopito K\u014drero<\/a>, a daily newsletter curated by our editors and delivered straight to your inbox every weekday.<\/p>\n","protected":false},"excerpt":{"rendered":"Embryo development. Photo: Supplied \/ Colossal Biosciences A multibillion-dollar de-extinction company believes it is one step closer to&hellip;\n","protected":false},"author":2,"featured_media":435144,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[48,47,111,43,139,69,49,46,44,45,147,406],"class_list":["post-435143","post","type-post","status-publish","format-standard","has-post-thumbnail","category-wildlife","tag-audio","tag-current-affairs","tag-new-zealand","tag-news","tag-newzealand","tag-nz","tag-podcasts","tag-public-radio","tag-radio-new-zealand","tag-rnz","tag-science","tag-wildlife"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/435143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=435143"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/435143\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/435144"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=435143"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=435143"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=435143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}