{"id":494014,"date":"2026-06-25T00:49:11","date_gmt":"2026-06-25T00:49:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/nz\/494014\/"},"modified":"2026-06-25T00:49:11","modified_gmt":"2026-06-25T00:49:11","slug":"revolution-medicines-to-present-clinical-data-from-rason","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/nz\/494014\/","title":{"rendered":"Revolution Medicines to Present Clinical Data from RAS(ON)"},"content":{"rendered":"<p align=\"justify\">REDWOOD CITY, Calif., June  24, 2026  (GLOBE NEWSWIRE) &#8212; Revolution Medicines, a late-stage clinical oncology company developing targeted therapies for patients with RAS-addicted cancers, today announced that four oral and poster presentations highlighting data from its RAS(ON) pipeline will be featured at the 2026 European Society for Medical Oncology (ESMO) Gastrointestinal Cancers Congress, taking place July 1\u20134, 2026 in Munich, Germany.<\/p>\n<p align=\"justify\">The program will include two oral presentations from Phase 1\/2 trials evaluating zoldonrasib, an oral RAS(ON) G12D-selective covalent inhibitor, in combination regimens for patients with metastatic RAS G12D pancreatic ductal adenocarcinoma (PDAC). These presentations will report results from zoldonrasib plus chemotherapy in the first line setting, and zoldonrasib plus daraxonrasib, the company\u2019s oral RAS(ON) multi-selective inhibitor, in patients who had received one or more prior lines of therapy.<\/p>\n<p align=\"justify\">Additional presentations will include two Phase 3 trials-in-progress posters for RASolute 303, evaluating daraxonrasib as a monotherapy or in combination with gemcitabine and nab-paclitaxel versus standard of care gemcitabine and nab-paclitaxel as a first line treatment for patients with metastatic PDAC, and RASolute 304, evaluating adjuvant daraxonrasib in patients with PDAC who have undergone resection and completed perioperative chemotherapy.<\/p>\n<p align=\"justify\">Details of Revolution Medicines\u2019 presentations are listed below.<\/p>\n<p align=\"justify\">Revolution Medicines Oral Presentations:<\/p>\n<p align=\"justify\">Revolution Medicines Posters:<\/p>\n<p align=\"justify\">About Revolution Medicines, Inc.<br \/>Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company\u2019s R&amp;D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company\u2019s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Additional development opportunities in the company\u2019s pipeline focus on RAS(ON) mutant-selective inhibitors, including RMC-0708 (Q61H) and RMC-8839 (G13C). For more information, please visit\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=kZENvMzWSyGgs5EKhR0B6ESJnBF4O5Fehes0y5p9j3aNZ5GtFjIuueNt7M06VnpB-tPjnwYKWN8tpQWF_utWqaHiA1nhPm84BM4w3SmJHAGJuZSRmHcNrY38-9hYEXfeq4YMCzzxD-7oNbF6DTcHqGbNkUT2coKsxboKN432jvP3jEyKBCERdsmx9sgaKsxoqxVF0jQg3ltjDELPeqlUcpYtroq1uw1DRPzfeepxY6tQYZ-g23UViyqKz_Fo_0Rt49CuavLdtg9BpRX5pcMCRTpQ0N7CI6b6Nhpj2Dx15K-79thw9xI80j57X8GMhaH1ggT0KGtrjMPPh9abTJqximP6gSHawtCDIar1e3YwcrB_4zCEDACCMCVlJmy-yUIPUcD8fMPCb4XzYOUoEj3hjt9wZsSnQi8Kspe88s_hjESzq5wFHcS0BKIYncPrjSTlsMyE_4jKV3IWFhgCKYDOMZmXCH6bUdOhKc8ta7cN1zormQk69majh_aH4fVo3STBui3uhGT2E2SXpmWURl-H8XgoU9XpA-QcUMWQd8ObeQUqnovESnawceFISitv-HFnswI9hkYJUcb-sdQRnH8bM91zScA-ZWhYjtDf9PFb_y32qhylbRD2qjKU1KOziSUHesdFR1fF3u7vCKqISMuJtY3p0dpdQxID5xblO0n2ZQVHlcU5frUOf16cVFBe0PPhMdXJ1b4NGxHNacvktdLqmQ==\" rel=\"nofollow noopener\" target=\"_blank\" title=\"www.revmed.com\">www.revmed.com<\/a>\u00a0and follow us on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=5grsKGUtftrn3pQZM5a8bAilQcWOPCRPWbvGu41U825F24cdF_BGLQY3cueL-RinNt_Zb5UAZoo9TqKzlYBUl_uVYYXEt8vBVMjNVfF1ju9VmiBEXQ26QGQKeFBsMRB_GyRCga0ZnZeVf6pLNsopniD2FfqvnA0LUsS32M-sjxRB4zPHvKw4vuLhyyMuTCkz3RCFtxreD1r07FTqk24_Vj8IZ6JHquv_Z_M5uj9EhrAbjHgBjDSuFGPaNLGyDHYCOh-GzBoLjaLG9PtBD1tulfay_D0V6csOqqHOebIWSh231Zwd8xegRsVa0GBznvsIJoIJn-Z_IeYN34tmrskqSX68tQbo6d03NlWjdhNUExAKkZlRC8RTftcG66-5DgMtKKZFChGtfxoPr2vvixnT0kkB9Gp56B2wQcDDyJOJyUckGv6Ai0-SEMBZCMICQhY95ZHNZXtbC3hHtAQICKay6szv2fjQqsa2iM1CfEItZgGbaYL5uTPkOrJQyLIkivYp16A0B-lSahdeC3-1NWhBBXUueabvd2w7niiWFLoGZJrC2wZpU9VQ3LIOBccNMS8erHWnoog6-HNMJ9TUX9YUeE1efi9P0ClWc8iktg17BM6LRSDnTGIxc1i9jff6kdxvcUmLVNo0sd6BDq5oy5xoYRDglL7_YOO_lv9ByZ_F4ElCRE3PbTwhIF3uIDpCNt4FO9iaT_LBhHuANWzRv_wGnhSpuQ1AzfZCHIUPJ6sAGxFP6M4rPOw1iAqOVNWf0Fyf\" rel=\"nofollow noopener\" target=\"_blank\" title=\"LinkedIn\">LinkedIn<\/a>.<\/p>\n<p align=\"justify\">Forward Looking Statements\u00a0<\/p>\n<p>This press release contains forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Any statements in this press release that are not historical facts may be considered \u201cforward-looking statements,\u201d including without limitation statements regarding the progression of clinical studies and findings from these studies, including the tolerability, safety, and potential efficacy of the company\u2019s candidates being studied.<\/p>\n<p align=\"justify\">Forward-looking statements are typically, but not always, identified by the use of words such as \u201caims,\u201d \u201canticipate,\u201d &#8220;believe,&#8221; &#8220;estimate,&#8221; &#8220;expect,&#8221; &#8220;plan,&#8221; \u201cpotential,\u201d \u201cproject,\u201d \u201cup to,\u201d &#8220;will&#8221; and other similar terminology indicating future results. Such forward-looking statements are subject to substantial risks and uncertainties that could cause the company\u2019s development programs, future results, performance, or achievements to differ materially from those anticipated in the forward-looking statements. Such risks and uncertainties include without limitation risks and uncertainties inherent in the drug development process, including the company\u2019s programs\u2019 development stages, the process of designing and conducting preclinical and clinical trials, the regulatory approval processes, the timing of regulatory filings, the challenges associated with manufacturing drug products, the company\u2019s ability to successfully establish, protect and defend its intellectual property, other matters that could affect the sufficiency of the company\u2019s capital resources to fund operations, reliance on third parties for manufacturing and development efforts, changes in the competitive landscape, and the effects on the company\u2019s business of the global events, such as international conflicts or global pandemics. For a further description of the risks and uncertainties that could cause actual results to differ from those anticipated in these forward-looking statements, as well as risks relating to the business of Revolution Medicines in general, see Revolution Medicines\u2019 Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission (the \u201cSEC\u201d) on May 6, 2026, and its future periodic reports to be filed with the SEC. Except as required by law, Revolution Medicines undertakes no obligation to update any forward-looking statements to reflect new information, events, or circumstances, or to reflect the occurrence of unanticipated events.<\/p>\n<p>Revolution Medicines Media &amp; Investor Contact:\u00a0<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=m-H_7OoFJO_gMMWzatJQSC8mlVnOgPBCKqQ35_EvRT0Oz2hmuwB28ORZPoDl-4ydKqr8DokV_tPg5_HUXct6X_07gtCJL9b8KbQDBG_cGiI=\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\">media@revmed.com<\/a>\u00a0\u00a0<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=svHJb-8qm1lVG6EjZNBBKVXmmOS5Y2f6GnqfJAzedvSOKveNAzbVI-IoWveVf61TtABbuDT4lMFi2fGpTYLusmlNbPkfkp0jej_Vz5lZOdPsl2U96wukh1JzRDkx8mqFGORPR6iZKBlwekgzxadQ40NDM7cdIgsIrWFLAJ9HhFJGVAdnNe2sBSf5iv8FH_hBEXuieGdImeyw-OYmMn3AsVPHMv8frohU9yJaVEa2dpIOG9UU7CQXejAtYhMjQLpzJeItlgP_3JVQnqcPzcOVvQ==\" rel=\"nofollow noopener\" target=\"_blank\" title=\"\">investors@revmed.com<\/a>\u00a0<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/06\/Revolution-Medicines-Inc-.png\" referrerpolicy=\"no-referrer-when-downgrade\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"REDWOOD CITY, Calif., June 24, 2026 (GLOBE NEWSWIRE) &#8212; Revolution Medicines, a late-stage clinical oncology company developing targeted&hellip;\n","protected":false},"author":2,"featured_media":494015,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[247371,2534,134,420,247373,247370,111,139,69,6840,247372,135936],"class_list":["post-494014","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-rvmd","tag-cancer","tag-health","tag-inc","tag-kras","tag-nasdaqrvmd","tag-new-zealand","tag-newzealand","tag-nz","tag-oncology","tag-ras","tag-revolution-medicines"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/494014","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=494014"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/494014\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/494015"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=494014"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=494014"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=494014"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}