{"id":629701,"date":"2026-10-13T21:50:09","date_gmt":"2026-10-13T21:50:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/nz\/629701\/"},"modified":"2026-10-13T21:50:09","modified_gmt":"2026-10-13T21:50:09","slug":"diego-diaz-garcia-aeneas2-explores-treatment-sequencing-in-egfr-mutated-nsclc","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/nz\/629701\/","title":{"rendered":"Diego D\u00edaz Garc\u00eda: AENEAS2 Explores Treatment Sequencing in EGFR-Mutated NSCLC"},"content":{"rendered":"<p> Diego D\u00edaz Garc\u00eda, Medical Oncologist, CEO and Founder of C\u00e1nCare, shared on <a href=\"https:\/\/x.com\/diegoadiazg\/status\/2109878587855671725\" rel=\"nofollow\">X<\/a>:<\/p>\n<p>\u201cAENEAS2: aumolertinib + chemotherapy in EGFR+ NSCLC \u2013 The combination improved PFS vs aumolertinib alone:<\/p>\n<p>PFS: 28.9 vs 18.9 months<br \/>\nHR 0.47; 95% CI 0.37-0.60; P&lt;0.0001<br \/>\nG3-4 Neutropenia: 55% vs 1%<\/p>\n<p>Significant benefit in PFS, with greater hematological toxicity. OS pending follow-up.\u201d<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-607833\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/10\/HUfLZL-W0AAUaVF-800x380.webp\" alt=\"Diego D\u00edaz Garc\u00eda\" width=\"800\" height=\"380\" title=\"Diego D\u00edaz Garc\u00eda: AENEAS2 Explores Treatment Sequencing in EGFR-Mutated NSCLC 2\"  \/><\/p>\n<p>Title: Aumolertinib with or without chemotherapy in EGFR-mutated advanced non-small-cell lung cancer (AENEAS2): an open-label, multicentre, randomised, controlled, phase 3 trial<\/p>\n<p>Authors: Ziming Li, Jie Hu, Jianhua Chen, Yan Yu, Xiangjiao Meng, Xiaorong Dong, Yanping Hu, Yinghua Ji, Haifeng Liu, Weibo Wang, Fangling Ning, Zhihong Zhang, Chunling Liu, Zhiye Zhang, Qiming Wang, Wei Zheng, Honghai Wang, Xiujuan Qu, Zhenming Chen, Shaonan Fan, Xiaoqing Zhangu, Shun Lu.<\/p>\n<p>Read <a href=\"https:\/\/www.thelancet.com\/journals\/lanonc\/article\/PIIS1470-2045(26)00090-2\/abstract\" target=\"_blank\" rel=\"noopener nofollow\">the full article<\/a>.<\/p>\n<p>You can also read:<\/p>\n<p><a href=\"https:\/\/oncodaily.com\/oncolibrary\/lung-oncology\/hong-kong-model\" rel=\"nofollow noopener\" target=\"_blank\">Hong Kong Model Finds EGFR\/ALK-First Testing More Cost-Efficient Than Upfront NGS in Metastatic NSCLC<\/a><\/p>\n<p><a href=\"https:\/\/oncodaily.com\/oncolibrary\/lung-oncology\/hong-kong-model\" rel=\"nofollow noopener\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-607847\" src=\"https:\/\/www.newsbeep.com\/nz\/wp-content\/uploads\/2026\/10\/Lung-82-1-1-800x450.webp\" alt=\"Diego D\u00edaz Garc\u00eda: AENEAS2 Explores Treatment Sequencing in EGFR-Mutated NSCLC\" width=\"800\" height=\"450\" title=\"Diego D\u00edaz Garc\u00eda: AENEAS2 Explores Treatment Sequencing in EGFR-Mutated NSCLC 3\"  \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Diego D\u00edaz Garc\u00eda, Medical Oncologist, CEO and Founder of C\u00e1nCare, shared on X: \u201cAENEAS2: aumolertinib + chemotherapy in&hellip;\n","protected":false},"author":2,"featured_media":629702,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[134,111,139,69],"class_list":["post-629701","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-new-zealand","tag-newzealand","tag-nz"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/629701","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=629701"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/629701\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/629702"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=629701"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=629701"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=629701"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}