{"id":640341,"date":"2026-10-24T22:10:08","date_gmt":"2026-10-24T22:10:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/nz\/640341\/"},"modified":"2026-10-24T22:10:08","modified_gmt":"2026-10-24T22:10:08","slug":"idweek-2026-contagion-live-asuptegravir-lowers-hiv-1-rna-up-to-2-36-logs-in-early-monotherapy","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/nz\/640341\/","title":{"rendered":"[IDWeek 2026] Contagion Live | Asuptegravir lowers HIV-1 RNA up to 2.36 logs in early monotherapy"},"content":{"rendered":"<p>Contagion Live news story<\/p>\n<p class=\"\">Asuptegravir (Jiangsu Aidea Pharmaceutical), an investigational integrase strand transfer inhibitor, reduced HIV-1 RNA by 1.49 to 2.36 log10 copies\/mL after 10 days of monotherapy in treatment-naive people with HIV, with a clear dose-response relationship. Hong Qin, MD, PhD, chief medical officer of Aidea, presented phase 1 and phase 1\/2 data at IDWeek 2026, held October 21-24 in Washington, DC. A third poster reported final 48-week results from the RECOVER study of fostemsavir in immunologic nonresponders.<\/p>\n<p class=\"\">Asuptegravir is metabolized by UGT1A1 and is being evaluated alongside emtricitabine and tenofovir alafenamide. Immunologic nonresponders, defined as people with CD4+ T-cell counts persistently below 350 cells\/mm3 despite at least 2 years of viral suppression, face higher risks of AIDS progression, non-AIDS events, and death.<\/p>\n<p>Read the full news story <a href=\"https:\/\/www.contagionlive.com\/view\/asuptegravir-lowers-hiv-1-rna-2-36-logs-early-monotherapy\" target=\"_blank\" rel=\"noopener nofollow\">here<\/a>.<a href=\"https:\/\/www.contagionlive.com\/conference\/idweek\" target=\"_blank\" rel=\"noopener nofollow\">View all Contagion Live reports from IDWeek 2026<\/a><\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"Contagion Live news story Asuptegravir (Jiangsu Aidea Pharmaceutical), an investigational integrase strand transfer inhibitor, reduced HIV-1 RNA by&hellip;\n","protected":false},"author":2,"featured_media":640342,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[134,111,139,69],"class_list":["post-640341","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-new-zealand","tag-newzealand","tag-nz"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/640341","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=640341"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/640341\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/640342"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=640341"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=640341"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=640341"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}