{"id":646451,"date":"2026-10-31T02:00:14","date_gmt":"2026-10-31T02:00:14","guid":{"rendered":"https:\/\/www.newsbeep.com\/nz\/646451\/"},"modified":"2026-10-31T02:00:14","modified_gmt":"2026-10-31T02:00:14","slug":"lupus-findings-open-new-paradigm-for-autoimmune-disease","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/nz\/646451\/","title":{"rendered":"Lupus findings open new paradigm for autoimmune disease"},"content":{"rendered":"<p>The researchers observed that the lupus patients in their study have encountered totally new abnormal peptides \u2013 tiny chains of amino acids \u2013 produced by aberrant splicing of their own messenger RNA. Messenger RNA acts as a liaison between the cell\u2019s DNA code and the places in a cell where proteins are made. mRNA brings in the instructions, then directs the manufacturing. <\/p>\n<p>\u201cThe importance of our finding is that they suggest the possibility of a completely new paradigm of autoimmune disease,\u201d said Dr. Tomas Mustelin, professor and head (Rheumatology) and co-senior author of the article reporting these results Oct. 29 in <a href=\"https:\/\/www.nature.com\/articles\/s41586-026-11219-7\" rel=\"nofollow noopener\" target=\"_blank\">Nature<\/a>. <\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"The researchers observed that the lupus patients in their study have encountered totally new abnormal peptides \u2013 tiny&hellip;\n","protected":false},"author":2,"featured_media":646452,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[134,111,139,69],"class_list":["post-646451","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-new-zealand","tag-newzealand","tag-nz"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/646451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/comments?post=646451"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/posts\/646451\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media\/646452"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/media?parent=646451"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/categories?post=646451"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/nz\/wp-json\/wp\/v2\/tags?post=646451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}