2025 FDA approvals
Drug developers secured approvals for 46 new therapeutic agents from the FDA’s Center for Drug Evaluation and Research…
Piperine suppresses M1 phenotype and induces indoleamine 2,3-dioxygenase gene in LPS-stimulated murine macrophage cell line | BMC Research Notes
Reagents RPMI-1640 medium and fetal bovine serum (FBS) were from Gibco (USA). Sigma-Aldrich (USA) supplied trypan blue, MTT,…
Opening the black box: defining true-negative outcomes in esophageal cancer screening — a population-based study | BMC Medicine
Parent study This prospective cohort study was based on the Endoscopic Screening for Esophageal Cancer in China (ESECC,…
Association between prostatic inflammation and detrusor overactivity in men with benign prostatic hyperplasia and bladder outlet obstruction: a prospective urodynamic and histological study
Roehrborn CG. Benign prostatic hyperplasia: an overview. Rev Urol. 2005;7:S3–14. PubMed PubMed Central Google Scholar Coyne KS, Sexton…
Intranasal vaccine combining adenovirus and trimeric subunit protein provides superior immunity against SARS-CoV-2 Omicron variant
The two-component intranasal vaccine elicits stronger humoral immunity To investigate the potential enhanced effects of combining the adenovirus…
Targeting MHC-E as a new strategy for vaccines and immunotherapeutics
Trowsdale, J. & Knight, J. C. Major histocompatibility complex genomics and human disease. Annu. Rev. Genom. Hum. Genet.…
In vivo genome editing of human haematopoietic stem cells for treatment of blood disorders using mRNA delivery
Esrick, E. B. et al. Post-transcriptional genetic silencing of BCL11A to treat sickle cell disease. N. Engl. J.…